What is the True Frequency of Carditis in Acute Rheumatic Fever? A Prospective Clinical and Doppler Blind Study of 56 Children with up to 60 Months of Follow-Up Evaluation

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dc.contributor.authorCaldas, Alvaro Manuel [UNIFESP]
dc.contributor.authorRamos Ascensao Terreri, Maria Teresa [UNIFESP]
dc.contributor.authorMoises, Valdir Ambrosio [UNIFESP]
dc.contributor.authorCamelo Silva, Celia Maria [UNIFESP]
dc.contributor.authorLen, Claudio Arnaldo [UNIFESP]
dc.contributor.authorCarvalho, Antonio Carlos [UNIFESP]
dc.contributor.authorEsteves Hilario, Maria Odete [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:51:50Z
dc.date.available2016-01-24T13:51:50Z
dc.date.issued2008-11-01
dc.description.abstractBackground This study aimed to evaluate prospectively clinical and echocardiographic findings of patients who had rheumatic fever with and without clinical features of cardiac involvement. Methods for this study, 56 consecutive patients (mean age, 11.4 years) with acute rheumatic fever diagnosed according to the 1992 modified Jones criteria were evaluated at diagnosis, after 3 and 6 months, then at 2 and 5 years. All assessments were performed blindly and included physical and cardiac examination, electrocardiogram, chest X-ray, and two-dimensional color-flow Doppler echocardiography. Results Initial clinical carditis was observed for 27 patients (48.2%), all of whom had positive echocardiographic abnormalities. Echocardiographic abnormalities were observed in 11 patients who had arthritis or chorea presentation without initial clinical carditis. Persistence of the abnormalities was observed at a late follow-up evaluation in 72.7% of the cases. Sydenham's chorea was present in 8 patients with clinical carditis and in 10 without this disorder, 8 of whom had echocardiographic abnormalities. Conclusion Patients who had acute rheumatic fever without clinical signs of carditis showed acute and late follow-up echocardiographic abnormalities suggestive of cardiac involvement. Clinicians should be attentive for the presence of cardiac involvement among patients with chorea.en
dc.description.affiliationUniversidade Federal de São Paulo, Div Allergy Clin Immunol & Rheumatol, BR-04025002 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Discipline Cardiol, Dept Med, BR-04025002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Allergy Clin Immunol & Rheumatol, BR-04025002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Discipline Cardiol, Dept Med, BR-04025002 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1048-1053
dc.identifierhttp://dx.doi.org/10.1007/s00246-008-9242-z
dc.identifier.citationPediatric Cardiology. New York: Springer, v. 29, n. 6, p. 1048-1053, 2008.
dc.identifier.doi10.1007/s00246-008-9242-z
dc.identifier.issn0172-0643
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30989
dc.identifier.wosWOS:000261069500005
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofPediatric Cardiology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectEchocardiographyen
dc.subjectJones criteriaen
dc.subjectRheumatic feveren
dc.subjectSubclinical carditisen
dc.subjectSydenham' choreaen
dc.titleWhat is the True Frequency of Carditis in Acute Rheumatic Fever? A Prospective Clinical and Doppler Blind Study of 56 Children with up to 60 Months of Follow-Up Evaluationen
dc.typeinfo:eu-repo/semantics/article
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