Reference Range of Embryo Volume by 3-D Sonography Using the XI VOCAL Method at 7 to 10+6 Weeks of Pregnancy

dc.contributor.authorAraujo Junior, Edward [UNIFESP]
dc.contributor.authorMachado Nardozza, Luciano Marcondes [UNIFESP]
dc.contributor.authorRolo, Liliam Cristine [UNIFESP]
dc.contributor.authorNowak, Paulo Martin [UNIFESP]
dc.contributor.authorBortoletti Filho, Joao [UNIFESP]
dc.contributor.authorMoron, Antonio Fernandes [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:59:46Z
dc.date.available2016-01-24T13:59:46Z
dc.date.issued2010-06-01
dc.description.abstractWe sought to establish normative data for three-dimensional ultrasound (3DUS) first-trimester embryonic volume using the extended imaging virtual organ computer-aided analysis (XI VOCAL) technique. This cross-sectional study involved 64 normal pregnancies at 7 to 10 + 6 weeks' gestation. Embryonic volume was obtained on 3DUS using the XI VOCAL technique with manual outline of 10 sequential planes. the mean, median, standard deviation, and maximum and minimum values were obtained for each week calculated. Polynomial regression models adjusted by the determination coefficient (R(2)) were created to assess the correlation between embryonic volume and gestational age (GA) and crown rump length (CRL). the intraclass correlation coefficient (ICC) was used to calculate inter-and intraobserver reproducibility. Mean embryonic volume went from 0.20 cm(3) (range 0.10 to 0.89 cm(3)) to 5.12 cm(3) (range 2.90 to 5.98 cm(3)). Embryonic volume was strongly correlated with GA (R(2) = 0.84) and with CRL (R(2) = 0.87). There was a good inter-and intraobserver reproducibility of embryonic volume with ICC = 0.999 and 0.995, respectively. Reference range for 3DUS first-trimester embryonic volume using the XI VOCAL technique were generated for pregnancies at 7 to 10 + 6 weeks, with high inter-and intraobserver reproducibility.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent501-505
dc.identifierhttp://dx.doi.org/10.1055/s-0030-1247607
dc.identifier.citationAmerican Journal of Perinatology. New York: Thieme Medical Publ Inc, v. 27, n. 6, p. 501-505, 2010.
dc.identifier.doi10.1055/s-0030-1247607
dc.identifier.issn0735-1631
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/32603
dc.identifier.wosWOS:000278013400011
dc.language.isoeng
dc.publisherThieme Medical Publ Inc
dc.relation.ispartofAmerican Journal of Perinatology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectFirst trimester of pregnancyen
dc.subjectembryoen
dc.subjectvolume measurementen
dc.subjectthree-dimensional ultrasonographyen
dc.subjectnomogramen
dc.titleReference Range of Embryo Volume by 3-D Sonography Using the XI VOCAL Method at 7 to 10+6 Weeks of Pregnancyen
dc.typeinfo:eu-repo/semantics/article
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