Immobilization of Amano lipase from Pseudomonas fluorescens on silk fibroin spheres: an alternative protocol for the enantioselective synthesis of halohydrins
dc.citation.issue | 21 | |
dc.citation.volume | 7 | |
dc.contributor.author | Ferreira, Irlon Maciel [UNIFESP] | |
dc.contributor.author | Yoshioka, Sergio A. | |
dc.contributor.author | Comassetode, Joao V. [UNIFESP] | |
dc.contributor.author | Porto, Andre L. M. | |
dc.coverage | Cambridge | |
dc.date.accessioned | 2020-07-31T12:46:52Z | |
dc.date.available | 2020-07-31T12:46:52Z | |
dc.date.issued | 2017 | |
dc.description.abstract | The search for a new, efficient, cheaper and sustainable matrix for lipase immobilization is a growing area in biotechnology. Amano lipase from Pseudomonas fluorescens was immobilized on silk fibroin spheres and used in the enzymatic kinetic resolution of halohydrins, to obtain optically active epoxides (up to 99% ee), important precursors in the synthesis of derivative antifungal azoles. This paper reinforces the versatility of silk fibroin as a support for heterogeneous catalysts. | en |
dc.description.affiliation | Univ Fed Sao Carlos, Inst Quim Sao Carlos, Ave Joao Dagnone, Ed Quim Ambiental, BR-13563120 Sao Carlos, Brazil | |
dc.description.affiliation | Univ Fed Amapa, Grp Biocatalise & Biotransformacao Quim Organ, Rod Juscelino Kubitscheck,KM 02 S-N, BR-68903419 Macapa, AP, Brazil | |
dc.description.affiliation | Univ Sao Paulo, Inst Quim Sao Carlos, Lab Bioquim & Biomat, Ave Trabalhador Sao Carlense 400, BR-13560970 Sao Carlos, SP, Brazil | |
dc.description.affiliation | Univ Sao Paulo, Inst Quim, Ave Prof Lineu Prestes 748, BR-05508000 Sao Paulo, SP, Brazil | |
dc.description.affiliation | Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Ave Prof Artur Riedel 275, BR-09972270 Diadema, SP, Brazil | |
dc.description.affiliationUnifesp | Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Av. Prof. Artur Riedel, 275, 09972-270 Diadema, Brazil | |
dc.description.source | Web of Science | |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.description.sponsorshipID | CNPq: 558062/2009-1 | |
dc.description.sponsorshipID | CNPq: 558062/2009-1 | |
dc.description.sponsorshipID | FAPESP: 2009/50688-3 | |
dc.format.extent | 12650-12658 | |
dc.identifier | http://dx.doi.org/10.1039/c7ra00083a | |
dc.identifier.citation | Rsc Advances. Cambridge, v. 7, n. 21, p. 12650-12658, 2017. | |
dc.identifier.doi | 10.1039/c7ra00083a | |
dc.identifier.file | WOS000395934500026.pdf | |
dc.identifier.issn | 2046-2069 | |
dc.identifier.uri | https://repositorio.unifesp.br/handle/11600/56425 | |
dc.identifier.wos | WOS:000395934500026 | |
dc.language.iso | eng | |
dc.publisher | Royal Soc Chemistry | |
dc.relation.ispartof | Rsc Advances | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.title | Immobilization of Amano lipase from Pseudomonas fluorescens on silk fibroin spheres: an alternative protocol for the enantioselective synthesis of halohydrins | en |
dc.type | info:eu-repo/semantics/article |
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