What do Cochrane systematic reviews say about interventions for vitamin D supplementation?

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dc.citation.issue5
dc.citation.volume135
dc.contributor.authorMateussi, Mariana Vendramin [UNIFESP]
dc.contributor.authorCruz Latorraca, Carolina de Oliveira [UNIFESP]
dc.contributor.authorDaou, Julia Pozetti [UNIFESP]
dc.contributor.authorCabrera Martimbianco, Ana Luiza [UNIFESP]
dc.contributor.authorRiera, Rachel [UNIFESP]
dc.contributor.authorPacheco, Rafael Leite [UNIFESP]
dc.contributor.authorPachito, Daniela Vianna [UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-08-04T13:40:15Z
dc.date.available2020-08-04T13:40:15Z
dc.date.issued2017
dc.description.abstractCONTEXT AND OBJECTIVE: Despite the high prevalence of vitamin D supplementation, its use remains controversial. The objective of this review was to identify and summarize the evidence from Cochrane systematic reviews regarding vitamin D supplementation for preventing or treating any clinical condition. DESIGN AND SETTING: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: A search was conducted to identify all Cochrane systematic reviews that fulfilled the inclusion criteria. Titles and abstracts were screened by two authors. RESULTS: We included 27 Cochrane systematic reviews: 10 assessing use of vitamin D for prevention and 17 for treatment. The reviews found moderate to high quality of evidence regarding the benefit of vitamin D for pregnant women (prevention of adverse events: preterm birth risk [rate ratio, RR 0.36en
dc.description.abstract95% confidence interval, CI 0.14 to 0.93] and low birthweight risk [RR 0.40en
dc.description.abstract95% CI 0.24 to 0.67]) and for asthma patients (reduction of severe exacerbations [RR 0.63en
dc.description.abstract95% CI 0.45 to 0.88]). No benefit was found regarding vitamin D supplementation alone (without calcium) for preventing hip or any new fracture. For all other outcomes assessed under various conditions, the current quality of evidence is low or unknown, and therefore insufficient for any recommendation. CONCLUSION: Based on moderate to high quality of evidence, the Cochrane systematic reviews included here showed that there were some benefits from vitamin D supplementation for pregnant women and asthma patients and no benefits for preventing fractures.en
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Hlth, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo Unifesp, Postgrad Evidence Based Hlth Program, Sao Paulo, SP, Brazil
dc.description.affiliationCochrane Brazil, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Hlth, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo Unifesp, Postgrad Evidence Based Hlth Program, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent497-507
dc.identifierhttp://dx.doi.org/10.1590/1516-3180.2017.0230150817
dc.identifier.citationSao Paulo Medical Journal. Sao Paulo, v. 135, n. 5, p. 497-507, 2017.
dc.identifier.doi10.1590/1516-3180.2017.0230150817
dc.identifier.fileS1516-31802017000500497.pdf
dc.identifier.issn1516-3180
dc.identifier.scieloS1516-31802017000500497
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57397
dc.identifier.wosWOS:000417223700014
dc.language.isoeng
dc.publisherAssociacao Paulista Medicina
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectReviewen
dc.subjectVitamin Den
dc.subjectEvidence-based medicineen
dc.subjectEvaluation of results of therapeutic interventionsen
dc.subjectEvidence-based practiceen
dc.titleWhat do Cochrane systematic reviews say about interventions for vitamin D supplementation?en
dc.typeinfo:eu-repo/semantics/article
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