Management of necrotizing scleritis after pterygium surgery with rituximab

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dc.contributor.authorde Alencar Fidelix, Tania Sales [UNIFESP]
dc.contributor.authorVieira, Luis Antonio [UNIFESP]
dc.contributor.authorMoca Trevisani, Virginia Fernandes [UNIFESP]
dc.date.accessioned2019-07-22T15:46:43Z
dc.date.available2019-07-22T15:46:43Z
dc.date.issued2016
dc.description.abstractThe authors present a case of necrotizing scleritis after pterygium excision successfully treated with rituximab after attempts with high doses of corticosteroids and immunosuppressive drugs. A literature review revealed case reports and a phase I/II dose-ranging randomized clinical trial using rituximab for necrotizing scleritis with or without association with autoimmune disease. This is the only case report on rituximab treatment for necrotizing scleritis after pterygium surgery. In cases with refractoriness to immunosuppressive drugs, a CD20 antibody can be used.en
dc.description.affiliationUniv Fed Sao Paulo, UNIFESP, Dept Oftalmol & Ciencias Visuais, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, UNIFESP, Dept Oftalmol & Ciencias Visuais, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent339-341
dc.identifierhttp://dx.doi.org/10.5935/0004-2749.20160097
dc.identifier.citationArquivos Brasileiros De Oftalmologia. Sao Paulo, v. 79, n. 5, p. 339-341, 2016.
dc.identifier.doi10.5935/0004-2749.20160097
dc.identifier.fileS0004-27492016000500339.pdf
dc.identifier.issn0004-2749
dc.identifier.scieloS0004-27492016000500339
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/51038
dc.identifier.wosWOS:000391431500016
dc.language.isoeng
dc.publisherConsel Brasil Oftalmologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectScleritisen
dc.subjectPterygium/surgeryen
dc.subjectRituximab/therapeutic useen
dc.subjectAntibodies, monoclonal/administration and dosageen
dc.titleManagement of necrotizing scleritis after pterygium surgery with rituximaben
dc.title.alternativeTratamento com rituximabe de esclerite necrosante após cirurgia de pterigeopt
dc.typeinfo:eu-repo/semantics/article
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