Human papillomavirus detected in viral warts of renal transplant recipients

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dc.citation.issue1
dc.citation.volume18
dc.contributor.authorMartelli-Marzagao, F. [UNIFESP]
dc.contributor.authorSantos Junior, G. F.
dc.contributor.authorOgawa, M. M. [UNIFESP]
dc.contributor.authorEnokihara, M. M. S. S. [UNIFESP]
dc.contributor.authorPorro, A. M. [UNIFESP]
dc.contributor.authorTomimori, J. [UNIFESP]
dc.coverageHoboken
dc.date.accessioned2020-10-30T18:46:27Z
dc.date.available2020-10-30T18:46:27Z
dc.date.issued2016
dc.description.abstractObjectivesFew studies have been conducted in South America regarding the detection and genotyping of human papillomavirus (HPV) in viral warts of renal transplant recipients (RTRs). The characterization of the population most susceptible to the development of warts and the knowledge of the main HPV types in this environment prompted this study, which focuses on the detection and typing of HPV in RTRs in Brazil. MethodsFifty-eight patients with viral warts from the Hospital SAo Paulo/Federal University of SAo Paulo were included in this study. HPV was detected by polymerase chain reaction (PCR) using combinations of the following primers: PGMY 09/11, RK 91, CP 65/70, and CP 66/69. Restriction fragment length polymorphism and automated sequencing techniques were used for HPV typing. ResultsHPV was detected by PCR in 89.7% of viral wart samples. The most frequently detected HPV types included 57, 27, 1a, 2a, and 20. Other types of HPV-epidermodysplasia verruciformis were also detected, including 14, 15, 19, 20, 21, 23, 36, and 38. Rare HPV types were also detected in our environment, including RTR X1, RTR X7, and 100. The time after transplant was correlated with an increased number of lesions and beta papillomavirus genus infection. ConclusionsThe HPV types detected in the RTR population were similar to those described in immunocompetent populations. However, the diversity of the HPV types identified and the number of lesions were increased in the RTR population.en
dc.description.affiliationUniv Fed Sao Paulo, UNIFESP, Dept Dermatol, Sao Paulo, Brazil
dc.description.affiliationAssoc Incent Funding Psychopharmacol, Lab Med, Dept Psychopharmacol, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Pathol, UNIFESP, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, UNIFESP, Dept Dermatol, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Pathol, UNIFESP, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent37-43
dc.identifierhttps://doi.org/10.1111/tid.12479
dc.identifier.citationTransplant Infectious Disease. Hoboken, v. 18, n. 1, p. 37-43, 2016.
dc.identifier.doi10.1111/tid.12479
dc.identifier.issn1398-2273
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/58470
dc.identifier.wosWOS:000370449800005
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofTransplant Infectious Disease
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectHPVen
dc.subjectrenal transplantationen
dc.subjectwartsen
dc.subjectimmunosuppressionen
dc.subjectpapillomavirusen
dc.titleHuman papillomavirus detected in viral warts of renal transplant recipientsen
dc.typeinfo:eu-repo/semantics/article
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