Quality of life on hemodialysis and inflammation: a descriptive analysis

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dc.citation.issue6
dc.citation.volume51
dc.contributor.authorBacci, M. R.
dc.contributor.authorAdami, F.
dc.contributor.authorFigueiredo, F. W. S.
dc.contributor.authorAlves, B. C. A.
dc.contributor.authorda Veiga, G. L.
dc.contributor.authorFonseca, F. L. A. [UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-07-02T18:51:51Z
dc.date.available2020-07-02T18:51:51Z
dc.date.issued2018
dc.description.abstractChronic kidney disease (CKD) is highly prevalent worldwide. Patients with CKD on hemodialysis are more likely to present behavioral changes and worse quality of life as a result of their routine and complications. They also have higher levels of cytokines. The aim of this study is to assess the relationship between the inflammatory profile and quality of life measured by KDOQL-SF36 in hemodialysis outpatients. Patients older than 21 years of age and on routine hemodialysis for at least 6 months with treatment on a regular weekly basis were included and their anthropometric parameters and serum inflammatory markers were evaluated. Thirty patients consented to participate. Homocysteine (Hcy) levels were correlated with worse glomerular filtration rate (GFRen
dc.description.abstractP=0.003) and creatinine (P=0.002). IL-6 was not correlated with worse nutritional status taking into account body mass index (BMIen
dc.description.abstractkg/m(2)en
dc.description.abstractP=0.83). On the other hand, TNF-alpha was positively correlated with albumin (P=0.008), nutritional status by BMI (P=0.04), and nutritional status by arm circumference area (P=0.04). IL-6 was correlated with activity limitation (P=0.02) and Hcy with work status (P=0.04). Hcy was correlated with nutritional status and inflammatory markers. In this population, the majority of the sections in KDOQL-SF36 were not correlated with cytokines levels.en
dc.description.affiliationFac Med ABC, Dept Clin Med, Santo Andre, SP, Brazil
dc.description.affiliationFac Med ABC, Lab Anal Clin, Santo Andre, SP, Brazil
dc.description.affiliationFac Med ABC, Lab Epidemiol & Anal Dados, Santo Andre, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Ciencias Farmaceut, Diadema, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ciencias Farmaceut, Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.1590/1414-431X20187355
dc.identifier.citationBrazilian Journal Of Medical And Biological Research. Sao Paulo, v. 51, n. 6, p. -, 2018.
dc.identifier.doi10.1590/1414-431X20187355
dc.identifier.fileWOS000430658900001.pdf
dc.identifier.issn0100-879X
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53755
dc.identifier.wosWOS:000430658900001
dc.language.isoeng
dc.publisherAssoc Bras Divulg Cientifica
dc.relation.ispartofBrazilian Journal Of Medical And Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectQuality of lifeen
dc.subjectHemodialysisen
dc.subjectInflammationen
dc.subjectHomocysteineen
dc.titleQuality of life on hemodialysis and inflammation: a descriptive analysisen
dc.typeinfo:eu-repo/semantics/article
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