Adolescent adaptive behavior profiles in Williams-Beuren syndrome, Down syndrome, and autism spectrum disorder

dc.citation.volume11]
dc.contributor.authorDel Cole, Carolina Grego [UNIFESP]
dc.contributor.authorCaetano, Sheila Cavalcante [UNIFESP]
dc.contributor.authorRibeiro, Wagner
dc.contributor.authorKummer, Arthur Melo E. E.
dc.contributor.authorJackowski, Andrea Parolin [UNIFESP]
dc.coverageLondon
dc.date.accessioned2020-06-26T16:30:14Z
dc.date.available2020-06-26T16:30:14Z
dc.date.issued2017
dc.description.abstractBackground: Adaptive behavior can be impaired in different neurodevelopmental disorders and may be influenced by confounding factors, such as intelligence quotient (IQ) and socioeconomic classification. Our main objective was to verify whether adaptive behavior profiles differ in three conditions-Williams Beuren syndrome (WBS), Down syndrome (DS), and autism spectrum disorder (ASD), as compared with healthy controls (HC) and with each other. Although the literature points towards each disorder having a characteristic profile, no study has compared profiles to establish the specificity of each one. A secondary objective was to explore potential interactions between the conditions and socioeconomic status, and whether this had any effect on adaptive behavior profiles. Methods: One hundred and five adolescents were included in the study. All adolescents underwent the following evaluations: the Vineland Adaptive Behavior Scale (VABS), the Wechsler Intelligence Scale for Children (WISC), and the Brazilian Economic Classification Criteria. Results: Our results demonstrated that the WBS group performed better than the DS group in the communication domain, beta = -15.08, t(3.45), p = .005, and better than the ASD group in the socialization domain, beta = 8.92, t(-2.08), p = .013. The DS group also performed better than the ASD group in socialization, beta = 16.98, t(-2.32), p = .024. IQ was an important confounding factor, and socioeconomic status had an important effect on the adaptive behavior of all groups. Conclusions: There is a heterogeneity regarding adaptive behavior profiles in WBS, DS, and ASD. These data are important to better design specific strategies related to the health and social care of each particular group.en
dc.description.affiliationUniv Fed Sao Paulo, LiNC, Dept Psiquiatria, Edificio Pesquisas 2 UNIFESP,Rua Pedro de Toledo, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, UPIA, Dept Psiquiatria, Rua Borges Lagoa,570-8 Andar Vila Clementino, Sao Paulo, SP, Brazil
dc.description.affiliationLondon Sch Econ & Polit Sci, Houghton St, London WC2A 2AE, England
dc.description.affiliationUniv Fed Minas Gerais, Dept Saude Mental, Av Prof Alfredo Balena,190 Sala 235, Belo Horizonte, MG, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, LiNC, Dept Psiquiatria, Edificio Pesquisas 2 UNIFESP,Rua Pedro de Toledo, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, UPIA, Dept Psiquiatria, Rua Borges Lagoa,570-8 Andar Vila Clementino, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
dc.description.sponsorshipIDCAPES: 7240705
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.1186/s13034-017-0177-0]
dc.identifier.citationChild And Adolescent Psychiatry And Mental Health. London, v. 11, p. -, 2017.
dc.identifier.doi10.1186/s13034-017-0177-0
dc.identifier.fileWOS000407234200001.pdf
dc.identifier.issn1753-2000
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53437
dc.identifier.wosWOS:000407234200001
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofChild And Adolescent Psychiatry And Mental Health
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleAdolescent adaptive behavior profiles in Williams-Beuren syndrome, Down syndrome, and autism spectrum disorderen
dc.typeinfo:eu-repo/semantics/article
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