Prevalence of Helicobacter pylori infection in an indigenous community in Sao Paulo and associated factors: cross-sectional study

Página do item simplificado
dc.citation.issue2
dc.citation.volume135
dc.contributor.authorda Silva Roque, Juliana Rejane [UNIFESP]
dc.contributor.authorMachado, Rodrigo Strehl [UNIFESP]
dc.contributor.authorRodrigues, Douglas [UNIFESP]
dc.contributor.authorRech, Patricia [UNIFESP]
dc.contributor.authorKawakam, Elisabete [UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-07-17T14:02:42Z
dc.date.available2020-07-17T14:02:42Z
dc.date.issued2017
dc.description.abstractCONTEXT AND OBJECTIVE: The prevalence of Helicobacter pylori infection is unevenly distributed among different populations. The aim here was to evaluate the factors associated with Helicobacter pylori infection among children up to five years of age living in a high-risk community. DESIGN AND SETTING: Cross-sectional study in an indigenous community of Guarani Mbya ethnicity, Tekoa Ytu and Tekoa Pyau villages, Jaragua district, city of Sao Paulo (SP), Brazil. METHODS: 74 children aged 0.4 to 4.9 years (mean 2.9 +/- 1.3 yearsen
dc.description.abstractmedian 3.1), and 145 family members (86 siblings, 43 mothers and 16 fathers) were evaluated for Helicobacter pylori infection using the validated C-13-urea breath test. Clinical and demographic data were collected. RESULTS: The prevalence was 8.3% among children aged 1-2 years and reached 64.3% among those aged 4-5 years (P = 0.018en
dc.description.abstractoverall 31.1%). The prevalence was 76.7% among siblings and 89.8% among parents. There was a negative association with previous use of antibiotics in multivariate analysis adjusted for age (odds ratio, OR: 0.07en
dc.description.abstract95% confidence interval, CI: 0.01 to 0.66en
dc.description.abstractP = 0.02). The prevalence was higher among males (OR: 1.55), and was associated with maternal infection (OR: 1.81), infection of both parents (OR: 1.5), vomiting (OR: 1.28), intestinal parasitosis (OR: 2.25), previous hospitalization (OR: 0.69) and breastfeeding (OR: 1.87). CONCLUSIONS: The prevalence was high among subjects older than three years of age, thus suggesting that the incidence of infection was higher over the first three years of life. Previous use of antibiotics was inversely associated with current Helicobacter pylori infection.en
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Dept Pediat, Discipline Pediat Gastroenterol, Rua Coronel Lisboa 826, BR-04020000 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Dept Prevent Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Dept Pediat, Discipline Pediat Gastroenterol, Rua Coronel Lisboa 826, BR-04020000 Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Dept Prevent Med, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
dc.description.sponsorshipIDFAPESP: 2010/51098-2
dc.format.extent140-145
dc.identifierhttp://dx.doi.org/10.1590/1516-3180.2016.0114091216
dc.identifier.citationSao Paulo Medical Journal. Sao Paulo, v. 135, n. 2, p. 140-145, 2017.
dc.identifier.doi10.1590/1516-3180.2016.0114091216
dc.identifier.fileWOS000402009700008.pdf
dc.identifier.issn1516-3180
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54963
dc.identifier.wosWOS:000402009700008
dc.language.isoeng
dc.publisherAssociacao Paulista Medicina
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPrevalenceen
dc.subjectHelicobacter pylorien
dc.subjectChilden
dc.subjectRisk factorsen
dc.subjectProtective factorsen
dc.titlePrevalence of Helicobacter pylori infection in an indigenous community in Sao Paulo and associated factors: cross-sectional studyen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
WOS000402009700008.pdf
Tamanho:
129.6 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Coleções
EPM - Artigos