Scale up of xylitol production from sugarcane bagasse hemicellulosic hydrolysate by Candida guilliermondii FTI 20037

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dc.citation.volume47
dc.contributor.authorde Arruda, Priscila Vaz [UNIFESP]
dc.contributor.authordos Santos, Julio Cesar
dc.contributor.authorLacerda Brambilla Rodrigues, Rita de Cassia
dc.contributor.authorVirginio da Silva, Debora Danielle
dc.contributor.authorYamakawa, Celina Kiyomi
dc.contributor.authorde Moraes Rocha, George Jackson
dc.contributor.authorNolasco Junior, Jonas
dc.contributor.authorda Cruz Pradella, Jose Geraldo
dc.contributor.authorVaz Rossell, Carlos Eduardo
dc.contributor.authorFelipe, Maria das Gracas de Almeida
dc.coverageNew York
dc.date.accessioned2020-07-17T14:02:38Z
dc.date.available2020-07-17T14:02:38Z
dc.date.issued2017
dc.description.abstractIn this study, volumetric oxygen mass transfer coefficient (kappa(L)a) was selected as a criterion for facilitating the scale up of xylitol production by Candida guilliermondii at the bench and pilot-scale level. A kappa(L)a value of 16 (h-1) was applied in reactors with volumetric capacity of 2.4 L, 18 L and 125 L Fermentation was successfully scaled-up from the bench to pilot-scale level with all experiments demonstrating a minimum of 60% xylose to xylitol conversion efficiency. Under all evaluated conditions glycerol and ethanol were also produced as by-products of xylose metabolism. Only minor differences were observed in the fermentation profile when reactor volumes ranging from 2.4 L to 125 L were used for experimentation purposes, reaching, at pilot scale, yield and volumetric productivity of 0.55 g g(-1) and 0.31 g L-1 h-1, respectively, with maximum specific growth rate of 0.26 h(-1). This demonstrates and reinforces the feasibility of using kLa as scale up criterion. The use of this parameter allowed precise reproduction of results obtained at bench bioreactor level to a larger scaleen
dc.description.abstractthis is extremely crucial and important information considering that the aim of the proposed biotechnological process is to reach the level required for the industrial viability. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.en
dc.description.affiliationFed Univ Sao Paulo UNIFESP, Dept Exact & Earth Sci, Campus Diadema, BR-09913030 Diadema, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Engn Sch Lorena, Dept Biotechnol, POB 116, BR-12602810 Lorena, SP, Brazil
dc.description.affiliationNatl Res Ctr Energy & Mat CNPEM, Brazilian Bioethanol Sci & Technol Lab CTBE, POB 6170, BR-13083970 Campinas, SP, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo UNIFESP, Dept Exact & Earth Sci, Campus Diadema, BR-09913030 Diadema, SP, Brazi
dc.description.sourceWeb of Science
dc.description.sponsorshipFAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo)
dc.description.sponsorshipCAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior)
dc.description.sponsorshipCNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico)
dc.description.sponsorshipIDFAPESP: 2010/51331-9
dc.format.extent297-302
dc.identifierhttp://dx.doi.org/10.1016/j.jiec.2016.11.046
dc.identifier.citationJournal Of Industrial And Engineering Chemistry. New York, v. 47, p. 297-302, 2017.
dc.identifier.doi10.1016/j.jiec.2016.11.046
dc.identifier.issn1226-086X
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54911
dc.identifier.wosWOS:000393929900033
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofJournal Of Industrial And Engineering Chemistry
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectSugarcane bagasseen
dc.subjectHemicellulosic hydrolysateen
dc.subjectXylitolen
dc.subjectScale upen
dc.subjectVolumetric oxygen mass transfer coefficienten
dc.titleScale up of xylitol production from sugarcane bagasse hemicellulosic hydrolysate by Candida guilliermondii FTI 20037en
dc.typeinfo:eu-repo/semantics/article
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