Calcium intake and its relationship with adiposity and insulin resistance in post-pubertal adolescents
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2008-04-01
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Background Dietary calcium intake has been described as being a negative contributor to adiposity. in adolescents, this relationship is not well established. the objectives of the present study were to compare the calcium intake of normal-weight and obese adolescents and to evaluate its relationship with adiposity and insulin resistance.Methods A cross-sectional analysis of 96 post-pubertal adolescents; 47 normal weight and 49 obese, mean age 16.6 (SD +/- 1.3) years. Body composition was assessed by dual-energy X-ray absorptiometry. Dietary intake was evaluated using a 3-day dietary record. the biochemical evaluation comprised the measurements of serum lipids, lipoproteins, glucose and insulin. Insulin resistance was calculated using the Homeostasis Model Assessment of Insulin resistance (HOMA-IR).Results the mean calcium intake, adjusted for energy, was lower in obese adolescents, 585.2 (+/- 249.9) mg, than in normal weight adolescents, 692.1 (+/- 199.5) mg. Only 4% of adolescents had an adequate intake of calcium. Calcium intake was inversely associated with body trunk fat, insulin and HOMA-IR in the obese group. the quartile analysis of calcium intake provided evidence that girls in the highest quartile had decreased adiposity and insulin resistance.Conclusions This study showed a negative relationship between calcium intake and body fat and insulin resistance, mainly in obese girls, and demonstrates the importance of an increased dietary calcium intake.
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Journal of Human Nutrition and Dietetics. Hoboken: Wiley-Blackwell, v. 21, n. 2, p. 109-116, 2008.