Voice Quality in Short Stature With and Without GH Deficiency

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dc.contributor.authorValenca, Eugenia H. O.
dc.contributor.authorSouza, Anita H. O.
dc.contributor.authorOliveira, Alaide H. A.
dc.contributor.authorValenca, Silvio L.
dc.contributor.authorSalvatori, Roberto
dc.contributor.authorGoncalves, Maria I. R. [UNIFESP]
dc.contributor.authorOliveira-Neto, Luiz A.
dc.contributor.authorBarros, Alana D.
dc.contributor.authorNascimento, Ualisson N.
dc.contributor.authorOliveira, Carla R. P.
dc.contributor.authorCardoso, Daniela F.
dc.contributor.authorMelo, Valdinaldo A.
dc.contributor.authorAguiar-Oliveira, Manuel H.
dc.contributor.institutionUniv Fed Sergipe
dc.contributor.institutionJohns Hopkins Univ
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:27:38Z
dc.date.available2016-01-24T14:27:38Z
dc.date.issued2012-09-01
dc.description.abstractObjective. the aim of this study was to analyze the individual impact of short stature (SS) or untreated isolated growth hormone deficiency (IGHD) on voice quality and the influence of IGHD on voice aging.Methods. A cross-sectional study was carried out on 73 adults: 33 IGHD, 10 SS, and 30 normal controls (CO), by evaluating vocal perception using Voice-Related Quality-of-Life (V-RQOL) scores and fundamental frequency (f(0)). Analysis of variance with Bonferroni post-test was used to compare groups, and the Student t test was used to verify the influence of aging.Results. Stature of the SS and IGHD groups was similarly reduced in comparison to CO. Cephalic perimeter (CP) in SS males was larger than CO (P < 0.05), and this was larger than in IGHD (P < 0.0001). CP was similar in SS and CO females, and both were larger than in IGHD (P < 0.0001). V-RQOL scores were lower in IGHD than in SS and CO. f(0) (Hz) was similar in IGHD females and SS and higher than in CO (P < 0.05). f(0) of IGHD males was higher than in SS (P = 0.01) and CO (P = 0.001). IGHD abolished the effect of aging on f(0) exhibited by CO.Conclusions. Lower vocal perception and higher f(0) were found in IGHD in comparison to CO in both genders; in comparison to SS, higher f(0) was only found in IGHD males. Because SS males have higher CP than IGHD, this suggests that CP and craniofacial growth can influence voice in IGHD. Finally, IGHD seems to abolish the effects of aging on voice.en
dc.description.affiliationUniv Fed Sergipe, Div Endocrinol, BR-49060100 Aracaju, Sergipe, Brazil
dc.description.affiliationUniv Fed Sergipe, Div Speech Therapy, BR-49060100 Aracaju, Sergipe, Brazil
dc.description.affiliationUniv Fed Sergipe, Div Dent, BR-49060100 Aracaju, Sergipe, Brazil
dc.description.affiliationUniv Fed Sergipe, Div Sci & Mat Engn, BR-49060100 Aracaju, Sergipe, Brazil
dc.description.affiliationJohns Hopkins Univ, Sch Med, Div Endocrinol, Baltimore, MD USA
dc.description.affiliationUniversidade Federal de São Paulo, Div Speech Therapy, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Speech Therapy, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent7
dc.identifierhttp://dx.doi.org/10.1016/j.jvoice.2011.12.009
dc.identifier.citationJournal of Voice. New York: Mosby-Elsevier, v. 26, n. 5, 7 p., 2012.
dc.identifier.doi10.1016/j.jvoice.2011.12.009
dc.identifier.issn0892-1997
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35231
dc.identifier.wosWOS:000308672400051
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Voice
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectGrowth hormone deficiencyen
dc.subjectShort statureen
dc.subjectQuality of lifeen
dc.subjectVoiceen
dc.titleVoice Quality in Short Stature With and Without GH Deficiencyen
dc.typeinfo:eu-repo/semantics/article
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