REGIONAL COOLING FOR REDUCING BRAIN TEMPERATURE AND INTRACRANIAL PRESSURE

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dc.contributor.authorForte, Luis Vicente [UNIFESP]
dc.contributor.authorPeluso, Cassio Morano [UNIFESP]
dc.contributor.authorPrandini, Mirto Nelso [UNIFESP]
dc.contributor.authorGodoy, Roberto
dc.contributor.authorRojas, Salomon Soriano Ordinola
dc.contributor.institutionHosp Sao Joaquim
dc.contributor.institutionHosp Meridional
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T14:00:15Z
dc.date.available2018-06-15T14:00:15Z
dc.date.issued2009-06-01
dc.description.abstractObjective: To evaluate the effectiveness of regional cooling for reducing brain temperature (BrTe) and intracranial pressure (ICP) in patients where conventional clinical treatment has failed. Method: Regional cooling was carried out using ice bags covering the area of the craniectomy (regional method) in 23 patients. The BrTe and ICP were determined using a fiber optic sensor. Thirteen patients (56.52%) were female. The ages ranged from 16 to 83 years (mean of 48.9). The mean APACHE II score was 25 points (11-35). The patients were submitted, on mean, to 61.7 hours (20-96) of regional cooling. Results: There was a significant reduction in mean BrTe (p<0.0001-from 37.1 degrees C to 35.2 degrees C) and mean ICP (p=0.0001-from 28 mmHg to 13 mmHg). Conclusion: Our results suggest that mild brain hypothermia induced by regional cooling was effective in the control of ICP in patients who had previously undergone decompressive craniectomy.en
dc.description.affiliationHosp Sao Joaquim, Real & Benemerita Soc Portuguesa Beneficencia Sao, Sao Paulo, Brazil
dc.description.affiliationHosp Meridional, Neurosurg Intens Care Unit, Cariacica, ES, Brazil
dc.description.affiliationUniv Fed Sao Paulo, UNIFESP, Dept Neurosurg, Escola Paulista Med, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, UNIFESP, Dept Neurosurg, Escola Paulista Med, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent480-487
dc.identifierhttp://dx.doi.org/10.1590/S0004-282X2009000300019
dc.identifier.citationArquivos De Neuro-psiquiatria. Sao Paulo Sp: Assoc Arquivos Neuro- Psiquiatria, v. 67, n. 2B, p. 480-487, 2009.
dc.identifier.doi10.1590/S0004-282X2009000300019
dc.identifier.fileS0004-282X2009000300019.pdf
dc.identifier.issn0004-282X
dc.identifier.scieloS0004-282X2009000300019
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/42749
dc.identifier.wosWOS:000268140200019
dc.language.isoeng
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.relation.ispartofArquivos De Neuro-psiquiatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectintracranial hypertensionen
dc.subjectintracranial pressureen
dc.subjectcerebral hypothermiaen
dc.subjectbrain edemaen
dc.subjectbrain injuriesen
dc.titleREGIONAL COOLING FOR REDUCING BRAIN TEMPERATURE AND INTRACRANIAL PRESSUREen
dc.title.alternativeResfriamento cerebral regional para redução da temperatura e pressão intracranianapt
dc.typeinfo:eu-repo/semantics/article
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