Premature rupture of membranes before 28 weeks managed expectantly: Maternal and perinatal outcomes in a developing country

dc.contributor.authorFernandes, G. L.
dc.contributor.authorTorloni, M. R.
dc.contributor.authorHisaba, W. Jou
dc.contributor.authorKlimke, D.
dc.contributor.authorNovaes, J.
dc.contributor.authorSancovski, M. [UNIFESP]
dc.contributor.authorPeixoto, S. [UNIFESP]
dc.contributor.institutionHosp Municipal Univ
dc.contributor.institutionFac Med ABC
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:17:47Z
dc.date.available2016-01-24T14:17:47Z
dc.date.issued2012-01-01
dc.description.abstractThis study aimed to assess outcomes of expectant management for early preterm premature rupture of membranes (PPROM). This retrospective cohort involved 66 women with PPROM <28 weeks managed in a single hospital (1999-2006). Main outcomes were chorioamnionitis, severe maternal morbidity (maternal sepsis, haemorrhage/blood transfusion, hysterectomy or admission to intensive care unit), maternal mortality, low birth weight, preterm birth, neonatal infection and perinatal mortality. Mean gestational ages at PPROM and delivery were 21.7 +/- 4.2 and 28.4 +/- 5.9 weeks, respectively. Chorioamnionitis was diagnosed in 47%; no cases of severe maternal morbidity or mortality occurred. Stillbirth rate was 25.7% and >80% of infants were delivered before 34 weeks. Neonatal infection was diagnosed in 42.9% of the 49 live-births. Overall survival rate was 57.6%. Expectant management of PPROM <28 weeks resulted in high rates of chorioamnionitis and preterm deliveries but in over half of the cases, a live infant was discharged home.en
dc.description.affiliationHosp Municipal Univ, High Risk Pregnancy Unit, Fac Med ABC, Sao Bernardo Do Campo, Brazil
dc.description.affiliationFac Med ABC, Dept Obstet, Santo Andre, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent45-49
dc.identifierhttp://dx.doi.org/10.3109/01443615.2011.609923
dc.identifier.citationJournal of Obstetrics and Gynaecology. New York: Informa Healthcare, v. 32, n. 1, p. 45-49, 2012.
dc.identifier.doi10.3109/01443615.2011.609923
dc.identifier.issn0144-3615
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34506
dc.identifier.wosWOS:000298295000013
dc.language.isoeng
dc.publisherInforma Healthcare
dc.relation.ispartofJournal of Obstetrics and Gynaecology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
dc.subjectDeveloping countriesen
dc.subjectmorbidityen
dc.subjectmortalityen
dc.subjectPPROMen
dc.titlePremature rupture of membranes before 28 weeks managed expectantly: Maternal and perinatal outcomes in a developing countryen
dc.typeinfo:eu-repo/semantics/article
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