Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures

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dc.citation.issue2
dc.citation.volume11
dc.contributor.authorPibarot, Philippe
dc.contributor.authorSimonato, Matheus [UNIFESP]
dc.contributor.authorBarbanti, Marco
dc.contributor.authorLinke, Axel
dc.contributor.authorKornowski, Ran
dc.contributor.authorRudolph, Tanja
dc.contributor.authorSpence, Mark
dc.contributor.authorMoat, Neil
dc.contributor.authorAldea, Gabriel
dc.contributor.authorMennuni, Marco
dc.contributor.authorIadanza, Alessandro
dc.contributor.authorAmrane, Hafid
dc.contributor.authorGaia, Diego [UNIFESP]
dc.contributor.authorKim, Won-Keun
dc.contributor.authorNapodano, Massimo
dc.contributor.authorBaumbach, Hardy
dc.contributor.authorFinkelstein, Ariel
dc.contributor.authorKobayashi, Junjiro
dc.contributor.authorBrecker, Stephen
dc.contributor.authorDon, Creighton
dc.contributor.authorCerillo, Alfredo
dc.contributor.authorUnbehaun, Axel
dc.contributor.authorAttias, David
dc.contributor.authorNejjari, Mohammed
dc.contributor.authorJones, Noah
dc.contributor.authorFiorina, Claudia
dc.contributor.authorTchetche, Didier
dc.contributor.authorPhilippart, Raphael
dc.contributor.authorSpargias, Konstantinos
dc.contributor.authorHernandez, Jose-Maria
dc.contributor.authorLatib, Azeem
dc.contributor.authorDvir, Danny
dc.coverageNew York
dc.date.accessioned2020-07-08T13:09:51Z
dc.date.available2020-07-08T13:09:51Z
dc.date.issued2018
dc.description.abstractOBJECTIVES The aim of this study was to determine whether the association of small label size of the surgical valve with increased mortality after transcatheter valve-in-valve (ViV) implantation is, at least in part, related to pre-existing prosthesis-patient mismatch (PPM) (i.e., a bioprosthesis that is too small in relation to body size). BACKGROUND Transcatheter ViV implantation is an alternative for the treatment of patients with degenerated bioprostheses. Small label size of the surgical valve has been associated with increased mortality after ViV implantation. METHODS Data from 1,168 patients included in the VIVID (Valve-in-Valve International Data) registry were analyzed. Pre-existing PPM of the surgical valve was determined using a reference value of effective orifice area for each given model and size of implanted prosthetic valve indexed for body surface area. Severe PPM was defined according to the criteria proposed by the Valve Academic Research Consortium 2: indexed effective orifice area <0.65 cm(2)/m(2) if body mass index is < 30 kg/m(2) and < 0.6 cm(2)/m(2) if BMI is >= 30 kg/m(2). The primary study endpoint was 1-year mortality. RESULTS Among the 1,168 patients included in the registry, 89 (7.6%) had pre-existing severe PPM. Patients with severe PPM had higher 30-day (10.3%, p = 0.01) and 1-year (unadjusted: 28.6%, p < 0.001 adjusted: 19.3%, p = 0.03) mortality rates compared with patients with no severe PPM (4.3%, 11.9%, and 10.9%, respectively). After adjusting for surgical valve label size, Society of Thoracic Surgeons score, renal failure, diabetes, and stentless surgical valves, presence of pre-existing severe PPM was associated with increased risk for 1-year mortality (odds ratio: 1.88 95% confidence interval: 1.07 to 3.28 p = 0.03). Patients with severe PPM also more frequently harbored high post-procedural gradients (mean gradient >= 20 mm Hg). CONCLUSIONS Pre-existing PPM of the failed surgical valve is strongly and independently associated with increased risk for mortality following ViV implantation. (C) 2018 by the American College of Cardiology Foundation.en
dc.description.affiliationInst Univ Cardiol & Pneumol Quebec, 2725 Chemin St Foy, Quebec City, PQ G1V 4G5, Canada
dc.description.affiliationEscola Paulista Med UNIFESP, Sao Paulo, Brazil
dc.description.affiliationFerraroto Hosp, Catania, Italy
dc.description.affiliationUniv Leipzig, Leipzig, Germany
dc.description.affiliationRabin Med Ctr, Petah Tiqwa, Israel
dc.description.affiliationUniklin Koln Herzzentrum, Cologne, Germany
dc.description.affiliationBelfast Hlth & Social Care Trust, Belfast, Antrim, North Ireland
dc.description.affiliationRoyal Brompton Harefield NHS Fdn Trust, London, England
dc.description.affiliationUniv Washington, Seattle, WA 98195 USA
dc.description.affiliationHumanitas Hosp, Milan, Italy
dc.description.affiliationUniv Senese, Azienda Osped, Siena, Italy
dc.description.affiliationMed Centrum Leeuwarden, Leeuwarden, Netherlands
dc.description.affiliationKerckhoff Klin, Bad Nauheim, Germany
dc.description.affiliationUniv Padua, Padua, Italy
dc.description.affiliationRobert Bosch Krankenhaus, Stuttgart, Germany
dc.description.affiliationTel Aviv Sourasky Med Ctr, Tel Aviv, Israel
dc.description.affiliationNatl Cerebral & Cardiovasc Ctr, Osaka, Japan
dc.description.affiliationSt Georges Univ London, London, England
dc.description.affiliationFdn Toscana Gabriele Monasterio, Pisa, Italy
dc.description.affiliationDeutsch Herzzentrum Berlin, Berlin, Germany
dc.description.affiliationCtr Cardiol Nord, St Denis, France
dc.description.affiliationMount Carmel Columbus, Columbus, OH USA
dc.description.affiliationSpedali Civili Brescia, Brescia, Italy
dc.description.affiliationClin Pasteur, Toulouse, France
dc.description.affiliationHygeia Hosp, Athens, Greece
dc.description.affiliationHospl Univ Virgen Victoria, Malaga, Spain
dc.description.affiliationOspede San Raffaele, Milan, Italy
dc.description.affiliationUnifespEscola Paulista Med UNIFESP, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCanadian Institutes of Health Research
dc.description.sponsorshipEdwards Lifesciences
dc.description.sponsorshipMedtronic
dc.description.sponsorshipAbbott
dc.description.sponsorshipIDCanadian Institutes of Health Research: FDN-143225
dc.format.extent133-141
dc.identifierhttp://dx.doi.org/10.1016/j.jcin.2017.08.039
dc.identifier.citationJacc-Cardiovascular Interventions. New York, v. 11, n. 2, p. 133-141, 2018.
dc.identifier.doi10.1016/j.jcin.2017.08.039
dc.identifier.issn1936-8798
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54255
dc.identifier.wosWOS:000422763200008
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofJacc-Cardiovascular Interventions
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectprosthesis-patient-mismatchen
dc.subjecttranscatheter aortic valve replacementen
dc.subjectvalve-in-valveen
dc.titleImpact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Proceduresen
dc.typeinfo:eu-repo/semantics/article
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