Improving survival among Brazilian children with perinatally-acquired AIDS

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dc.contributor.authorMatida, Luiza Harunari [UNIFESP]
dc.contributor.authorMarcopito, Luiz Francisco [UNIFESP]
dc.contributor.authorSucci, Regina Célia de Menezes [UNIFESP]
dc.contributor.authorMarques, Heloisa Helena de Souza
dc.contributor.authorDella Negra, Marinella
dc.contributor.authorGrangeiro, Alexandre
dc.contributor.authorHearst, Norman
dc.contributor.institutionSão Paulo State STD/AIDS Program
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversity of São Paulo
dc.contributor.institutionInfectious Disease Institute
dc.contributor.institutionNational STD/AIDS Program
dc.contributor.institutionUniversity of California
dc.date.accessioned2015-06-14T13:31:22Z
dc.date.available2015-06-14T13:31:22Z
dc.date.issued2004-12-01
dc.description.abstractBrazil was the first developing country to provide free, universal access to antiretroviral treatment for AIDS patients. The Brazilian experience thus provides the first evidence regarding the impact of such treatment on the survival of perinatally acquired AIDS cases in the developing world. MATERIAL AND METHODS: This retrospective cohort study used medical record reviews to examine characteristics and trends in the survival of a representative sample of 914 perinatally acquired AIDS cases in 10 Brazilian cities diagnosed between 1983 and 1998. RESULTS: Survival time increased steadily and substantially. Whereas half of the children died within 20 months of diagnosis at the beginning of the epidemic, 75% of children diagnosed in 1997 and 1998 were still alive after four years of follow-up. CONCLUSIONS: Advances in management and treatment have made a great difference in the survival of Brazilian children with AIDS. These results argue strongly for making such treatment available to children in the entire developing world.en
dc.description.affiliationSão Paulo State STD/AIDS Program
dc.description.affiliationFederal University of São Paulo
dc.description.affiliationUniversity of São Paulo
dc.description.affiliationInfectious Disease Institute
dc.description.affiliationNational STD/AIDS Program
dc.description.affiliationUniversity of California
dc.description.affiliationUnifespUNIFESP
dc.description.sourceSciELO
dc.format.extent419-423
dc.identifierhttp://dx.doi.org/10.1590/S1413-86702004000600005
dc.identifier.citationBrazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 8, n. 6, p. 419-423, 2004.
dc.identifier.doi10.1590/S1413-86702004000600005
dc.identifier.fileS1413-86702004000600005.pdf
dc.identifier.issn1413-8670
dc.identifier.scieloS1413-86702004000600005
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/2321
dc.language.isoeng
dc.publisherBrazilian Society of Infectious Diseases
dc.relation.ispartofBrazilian Journal of Infectious Diseases
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAcquired immunodeficiency syndromeen
dc.subjectBrazilen
dc.subjecthuman immunodeficiency virusen
dc.subjectpediatricen
dc.subjectperinatal transmissionen
dc.subjectsurvivalen
dc.titleImproving survival among Brazilian children with perinatally-acquired AIDSen
dc.typeinfo:eu-repo/semantics/article
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