Impact of influenza vaccination on civilian aircrew illness and absenteeism

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dc.contributor.authorMixeu, MSAG
dc.contributor.authorVespa, CNR
dc.contributor.authorForleo Neto, Eduardo [UNIFESP]
dc.contributor.authorToniolo Neto, João [UNIFESP]
dc.contributor.authorAlves, P. M.
dc.contributor.institutionRuben Berta Fdn VARIG
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionAventis Pasteur
dc.date.accessioned2018-06-15T14:00:18Z
dc.date.available2018-06-15T14:00:18Z
dc.date.issued2002-09-01
dc.description.abstractBackground: Approximately 10% of the general population worldwide acquires influenza infection every year. Airline crews run a particularly high risk of contracting influenza and influenza-like viruses because they come in contact with hundreds of potentially infected individuals every day. Respiratory diseases are the most frequent cause of absenteeism among flight crews in airline companies. Several studies have shown the efficacy of influenza vaccination in the workplace of healthy, working adults leading to increased productivity and lower absenteeism. We conducted a double blind, randomized, placebo-controlled study on flight crews of an airline company in order to determine the safety and efficacy of a trivalent inactivated influenza vaccine in reducing illness and absences from work. Methods: The 813 healthy members of a Brazilian airline company were randomly assigned to receive injections of either an influenza vaccine or a placebo, with a follow-up period of 7 mo after vaccination. Primary outcomes included influenza-like illness episodes and absenteeism from work due to such episodes. Results. Demographic characteristics were similar in the two groups. No significant side-effects occurred in either group, Compared to the placebo group, individuals receiving the vaccine showed 39.5% fewer episodes of flu-like illness (p < 0.001) and 26% fewer days of work lost (p = 0.03). The vaccinated group developed 33% fewer episodes of any severe flu-like illness (p < 0.01). Conclusion: The data indicates that influenza vaccination is safe in airline flight crews and may produce health-related benefits including reduced absenteeism.en
dc.description.affiliationRuben Berta Fdn VARIG, Med Serv, BR-04626020 Sao Paulo, Brazil
dc.description.affiliationRuben Berta Fdn VARIG, Med Serv, Rio De Janeiro, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Internal Med, Sao Paulo, Brazil
dc.description.affiliationAventis Pasteur, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Internal Med, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent876-880
dc.identifier.citationAviation Space And Environmental Medicine. Alexandria: Aerospace Medical Assoc, v. 73, n. 9, p. 876-880, 2002.
dc.identifier.issn0095-6562
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/42776
dc.identifier.wosWOS:000177802600005
dc.language.isoeng
dc.publisherAerospace Medical Assoc
dc.relation.ispartofAviation Space And Environmental Medicine
dc.rightsAcesso restrito
dc.subjectaircrew healthen
dc.subjectviral illnessen
dc.subjectrespiratory diseaseen
dc.subjectrandomized placebo-controlled trialen
dc.subjectabsenteeismen
dc.titleImpact of influenza vaccination on civilian aircrew illness and absenteeismen
dc.typeArtigo
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