Performance of adjuvant treatment correlates with survival in reoperated glioblastomas

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dc.citation.issue11
dc.citation.volume74
dc.contributor.authorZanovello, Willey Goncalves [UNIFESP]
dc.contributor.authorMalheiros, Suzana Maria Fleury [UNIFESP]
dc.contributor.authorStávale, João Norberto [UNIFESP]
dc.contributor.authorLanzoni, Oreste Paulo [UNIFESP]
dc.contributor.authorCanteras, Miguel Montes [UNIFESP]
dc.contributor.authorSantos, Adrialdo José [UNIFESP]
dc.contributor.authorSlaviero, Felipe [UNIFESP]
dc.contributor.authorFernandes, Bruno [UNIFESP]
dc.contributor.authorCavalheiro, Sergio [UNIFESP]
dc.contributor.authorPaiva Neto, Manoel Antonio de [UNIFESP]
dc.coverageSao Paulo Sp
dc.date.accessioned2020-07-31T12:47:25Z
dc.date.available2020-07-31T12:47:25Z
dc.date.issued2016
dc.description.abstractObjective: To analyze cases of recurrent glioblastoma subjected to reoperation at a Brazilian public healthcare service. Methods: A total of 39 patients subjected to reoperation for recurrent glioblastoma at the Department of Neurosurgery, Sao Paulo Hospital, Federal University of Sao Paulo, from January 2000 to December 2013 were retrospectively analyzed. Results: The median overall survival was 20 months (95% confidence interval -CI = 14.9-25.2), and the median survival after reoperation was 9.1 months (95% CI: 2.8-15.4). The performance of adjuvant treatment after the first operation was the single factor associated with overall survival on multivariate analysis (relative risk - RR = 0.3en
dc.description.abstract95% CI = 0.2-0.7)en
dc.description.abstractp = 0.005). Conclusion: The length of survival of patients subjected to reoperation for glioblastoma at a Brazilian public healthcare service was similar to the length reported in the literature. Reoperation should be considered as a therapeutic option for selected patients.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Neurocirurgia, Rua Leandro Dupret,847, BR-04025013 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Patol, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Departamento de Neurocirurgia, São Paulo SP, Brasil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Departamento de Patologia, São Paulo SP, Brasil
dc.description.sourceWeb of Science
dc.format.extent887-894
dc.identifierhttp://dx.doi.org/10.1590/0004-282X20160144
dc.identifier.citationArquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 74, n. 11, p. 887-894, 2016.
dc.identifier.doi10.1590/0004-282X20160144
dc.identifier.fileS0004-282X2016001100887.pdf
dc.identifier.issn0004-282X
dc.identifier.scieloS0004-282X2016001100887
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56817
dc.identifier.wosWOS:000388579300007
dc.language.isoeng
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.relation.ispartofArquivos De Neuro-Psiquiatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectglioblastomaen
dc.subjectreoperationen
dc.subjectgeneral surgeryen
dc.subjectsurvivalen
dc.titlePerformance of adjuvant treatment correlates with survival in reoperated glioblastomasen
dc.typeinfo:eu-repo/semantics/article
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