White adipose tissue re-growth after partial lipectomy in high fat diet induced obese Wistar rats

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dc.contributor.authorBueno, Allain Amador
dc.contributor.authorHabitante, Carlos Alexandre
dc.contributor.authorOyama, Lila Missae [UNIFESP]
dc.contributor.authorEstadella, Debora [UNIFESP]
dc.contributor.authorRibeiro, Eliane Beraldi [UNIFESP]
dc.contributor.authorNascimento, Claudia Maria da Penha Oller do [UNIFESP]
dc.contributor.institutionLondon Metropolitan Univ
dc.contributor.institutionUniv Fed de Mato Grosso
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:05:56Z
dc.date.available2016-01-24T14:05:56Z
dc.date.issued2011-01-01
dc.description.abstractThe effects of partial removal of epididymal (EPI) and retroperitoneal (RET) adipose tissues (partial lipectomy) on the triacylglycerol deposition of high fat diet induced obese rats were analyzed, aiming to challenge the hypothesized body fat regulatory system. Male 28-day-old wistar rats received a diet enriched with peanuts, milk chocolate and sweet biscuits during the experimental period. At the 90th day of life, rats were submitted to either lipectomy (L) or sham surgery. After 7 or 30 days, RET, EPI, liver, brown adipose tissue (BAT), blood and carcass were obtained and analyzed. Seven days following surgery, liver lipogenesis rate and EPI relative weight were increased in L. After 30 days, L, RET and EPI presented increased lipogenesis, lipolysis and percentage of small area adipocytes. L rats also presented increased liver malic enzyme activity, BAT lipogenesis, and triacylglycerol and corticosterone serum levels. the partial removal of visceral fat pads affected the metabolism of high fat diet obese rats, which leads to excised tissue regrowth and possibly compensatory growth of non-excised depots at a later time.en
dc.description.affiliationLondon Metropolitan Univ, Inst Brain Chem & Human Nutr, London N7 8DB, England
dc.description.affiliationUniv Fed de Mato Grosso, Inst Ciencias Biol & Saude, BR-78698 Pontal Do Araguaia, MT, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Fisiol, BR-04023060 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Fisiol, BR-04023060 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent55-63
dc.identifierhttps://dx.doi.org/10.1007/s12576-010-0122-y
dc.identifier.citationJournal of Physiological Sciences. Tokyo: Springer Tokyo, v. 61, n. 1, p. 55-63, 2011.
dc.identifier.doi10.1007/s12576-010-0122-y
dc.identifier.issn1880-6546
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/33266
dc.identifier.wosWOS:000289858400007
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofJournal of Physiological Sciences
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectPartial lipectomyen
dc.subjectHigh fat dieten
dc.subjectObesityen
dc.subjectAdipose tissueen
dc.subjectTriacylglycerol depositionen
dc.titleWhite adipose tissue re-growth after partial lipectomy in high fat diet induced obese Wistar ratsen
dc.typeinfo:eu-repo/semantics/article
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