Both human immunodeficiency virus-infected and human immunodeficiency virus-exposed, uninfected children living in Brazil, Argentina, and Mexico have similar rates of low concentrations of retinol, beta-carotene, and vitamin E

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dc.contributor.authorMonteiro, Jacqueline P.
dc.contributor.authorFreimanis-Hance, Laura
dc.contributor.authorFaria, Lidiane B.
dc.contributor.authorMussi-Pinhata, Marisa M.
dc.contributor.authorKorelitz, James
dc.contributor.authorVannucchi, Helio
dc.contributor.authorQueiroz, Wladimir
dc.contributor.authorSucci, Regina C. M. [UNIFESP]
dc.contributor.authorHazra, Rohan
dc.contributor.institutionEunice Kennedy Shriver Natl Inst Child Hlth & Hum
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionWESTAT Corp
dc.contributor.institutionInst Infectol Emilio Ribas
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:58:48Z
dc.date.available2016-01-24T13:58:48Z
dc.date.issued2009-10-01
dc.description.abstractOur objective was to describe the prevalence of low concentrations of retinol, beta-carotene, and vitamin E in a group of human immunodeficiency virus (HIV)-infected Latin American children and a comparison group of HIV-exposed, uninfected children. Our hypothesis was that the rates of low concentrations of these micronutrients would be higher in the HIV-infected group than those in the HIV-exposed, uninfected group. This was a cross-sectional substudy of a larger cohort study at clinical pediatric HIV centers in Latin America. Serum levels of micronutrients were measured in the first stored sample obtained after each child's first birthday by high-performance liquid chromatography. Low concentrations of retinol, beta-carotene, and vitamin E were defined as serum levels below 0.70, 0.35, and 18.0 mu mol/L, respectively. the Population for this analysis was 336 children (124 HIV-infected, 212 HIV-exposed, uninfected) aged I year or older to younger than 4 years. Rates of low concentrations were 74% for retinol, 27% for beta-carotene, and 89% for vitamin E. These rates were not affected by HIV status. Among the HIV-infected children, those treated with anti retrovirals were less likely to have retinol deficiency, but no other HIV-related factors correlated with micronutrient low serum levels. Low concentrations of retinol, beta-carotene, and vitamin E are very common in children exposed to HIV living in Brazil, Argentina, and Mexico, regardless of HIV-infection status. Published by Elsevier Inc.en
dc.description.affiliationEunice Kennedy Shriver Natl Inst Child Hlth & Hum, Pediat Adolescent & Maternal AIDS Branch, Ctr Res Mothers & Children, NIH, Bethesda, MD 20892 USA
dc.description.affiliationUniv São Paulo, BR-14049 Ribeirao Preto, SP, Brazil
dc.description.affiliationWESTAT Corp, Rockville, MD 20850 USA
dc.description.affiliationInst Infectol Emilio Ribas, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipNICHD
dc.description.sponsorshipIDNICHD: N01-HD-3-3345
dc.description.sponsorshipIDNICHD: N01-DK-8-0001
dc.format.extent716-722
dc.identifierhttp://dx.doi.org/10.1016/j.nutres.2009.10.001
dc.identifier.citationNutrition Research. Oxford: Pergamon-Elsevier B.V., v. 29, n. 10, p. 716-722, 2009.
dc.identifier.doi10.1016/j.nutres.2009.10.001
dc.identifier.issn0271-5317
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/31864
dc.identifier.wosWOS:000272432000005
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofNutrition Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectbeta-caroteneen
dc.subjectChildrenen
dc.subjectHIVen
dc.subjectRetinolen
dc.subjectVitamin Een
dc.titleBoth human immunodeficiency virus-infected and human immunodeficiency virus-exposed, uninfected children living in Brazil, Argentina, and Mexico have similar rates of low concentrations of retinol, beta-carotene, and vitamin Een
dc.typeinfo:eu-repo/semantics/article
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