Egg donation of vitrified oocytes bank produces similar pregnancy rates by blastocyst transfer when compared to fresh cycle

Página do item simplificado
dc.citation.issue11
dc.citation.volume34
dc.contributor.authorDomingues, Thais S. [UNIFESP]
dc.contributor.authorAquino, Ana Paula
dc.contributor.authorBarros, Bruna
dc.contributor.authorMazetto, Raquel
dc.contributor.authorNicolielo, Mariana
dc.contributor.authorKimati, Carolina M.
dc.contributor.authorDevecchi, Talita
dc.contributor.authorBonetti, Tatiana C. S. [UNIFESP]
dc.contributor.authorSerafini, Paulo C.
dc.contributor.authorMotta, Eduardo L. A. [UNIFESP]
dc.coverageNew York
dc.date.accessioned2020-09-01T13:21:26Z
dc.date.available2020-09-01T13:21:26Z
dc.date.issued2017
dc.description.abstractPurpose Advances in reproductive techniques, mainly the introduction of oocyte vitrification, have provided the opportunity to conceive from oocyte banks. The aim of this study was to compare the clinical outcomes of fresh and vitrified oocytes in an egg donation program following blastocyst transfer. Methods This retrospective observational study included 504 oocyte donation cycles. All donor women were younger than 30 years of age. The recipient cycles were divided into two groups: fresh oocytes (n = 78) or vitrified oocytes (n = 426). All oocytes were fertilized by ICSI using ejaculated sperm, followed by blastocyst transfer. Endometrium preparation was performed with estradiol valerate plus micronized progesterone according to standard protocols. Results Recipients were of similar age (fresh 42.0 +/- 4.5 years vs vitrified 41.8 +/- 4.8 years; p = 0.790). The fresh group received more mature oocytes for injection compared to the vitrified group (10.1 +/- 2.8 vs 9.2 +/- 2.2; p = 0.005). The two pronuclei (2PN) rate (74.5 vs 77.4%; p = 0.195) and blastocyst rate (48.8 vs 51.6%; 0.329) were similar between the fresh and vitrified groups, respectively. The rates of clinical pregnancy were 60.9% in the fresh and 59.0% in the vitrified groups (p = 0.771). Conclusions Our findings suggest that vitrified oocytes result in similar pregnancy rates when compared to fresh oocytes with blastocyst transfer in an egg donation program. Moreover, vitrified oocytes may allow for a better cycle schedule, starting with a lower number of oocytes to be fertilized. Therefore, we hypothesize that egg banks with vitrified oocytes could be safely utilized in an egg donation program.en
dc.description.affiliationHuntington Med Reprodut, Av Republ Libano,529 Ibirapuera, BR-04501000 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, EPM, Dept Ginecol, Disciplina Ginecol Endocrinol, Rua Napoleao Barros,608 Vila Clementino, BR-04024002 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Fac Med, Dept Obstet & Ginecol, Disciplina Ginecol, Av Dr Arnaldo,455 Cerqueira Cesar, BR-01246903 Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, EPM, Dept Ginecol, Disciplina Ginecol Endocrinol, Rua Napoleao Barros,608 Vila Clementino, BR-04024002 Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent1553-1557
dc.identifierhttp://dx.doi.org/10.1007/s10815-017-1017-0
dc.identifier.citationJournal Of Assisted Reproduction And Genetics. New York, v. 34, n. 11, p. 1553-1557, 2017.
dc.identifier.doi10.1007/s10815-017-1017-0
dc.identifier.issn1058-0468
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/58259
dc.identifier.wosWOS:000416159300020
dc.language.isoeng
dc.publisherSpringer/Plenum Publishers
dc.relation.ispartofJournal Of Assisted Reproduction And Genetics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectOocyte donationen
dc.subjectOocyte vitrificationen
dc.subjectIn vitro fertilizationen
dc.subjectBlastocyst transferen
dc.subjectPregnancy ratesen
dc.titleEgg donation of vitrified oocytes bank produces similar pregnancy rates by blastocyst transfer when compared to fresh cycleen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos