Psychiatric disorders in juvenile myoclonic epilepsy: A controlled study of 100 patients

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dc.contributor.authorAraujo Filho, Gerardo Maria de
dc.contributor.authorPascalicchio, Tatiana F.
dc.contributor.authorSilva Sousa, Patricia da
dc.contributor.authorLin, Katia
dc.contributor.authorGuilhoto, Laura M. F. Ferreira
dc.contributor.authorYacubian, Elza Márcia Targas [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:48:40Z
dc.date.available2016-01-24T13:48:40Z
dc.date.issued2007-05-01
dc.description.abstractIn this controlled study we evaluated the frequency of psychiatric disorders (PDs) in 100 patients with juvenile myoclonic epilepsy (JME) and compared it with that of 100 healthy controls matched with respect to age, gender, schooling, and socioeconomic status. Our aim was to quantify the frequency of PDs and evaluate the relationship between PDs and factors related to epilepsy. Subjects were evaluated with the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I) and Axis II disorders (SCID-II). Patients with JME presented with significantly more PDs (P < 0.01) and psychosocial problems (P < 0.01) than the controls. PDs were diagnosed in 49 patients with JME. Anxiety and mood disorders, present in 23 and 19 patients, respectively, were the most frequently observed. Twenty patients fulfilled criteria for personality disorders; 17 (85%) patients had cluster B personalities comprising the behavioral characteristics impulsivity, humor reactivity, emotional instability, and difficulty in accepting social rules, similar to those cited in the earliest mentioned description of this syndrome. PDs were more frequently observed in patients with higher seizure frequency (P < 0.05). (C) 2007 Elsevier Inc. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Neurol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Neurol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent437-441
dc.identifierhttp://dx.doi.org/10.1016/j.yebeh.2007.01.016
dc.identifier.citationEpilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 10, n. 3, p. 437-441, 2007.
dc.identifier.doi10.1016/j.yebeh.2007.01.016
dc.identifier.issn1525-5050
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29716
dc.identifier.wosWOS:000246322200014
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofEpilepsy & Behavior
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectidiopathic generalized epilepsyen
dc.subjectjuvenile myoclonic epilepsyen
dc.subjectpersonality disordersen
dc.subjectpsychiatric disordersen
dc.subjectstructured clinical interview for DSM-IV disordersen
dc.titlePsychiatric disorders in juvenile myoclonic epilepsy: A controlled study of 100 patientsen
dc.typeinfo:eu-repo/semantics/article
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