Frontal Assessment Battery (FAB) is a simple tool for detecting executive deficits in chronic cannabis users

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dc.contributor.authorFontes, Maria Alice [UNIFESP]
dc.contributor.authorBolla, Karen I.
dc.contributor.authorCunha, Paulo Jannuzzi
dc.contributor.authorAlmeida, Priscila Previato [UNIFESP]
dc.contributor.authorJungerman, Flavia [UNIFESP]
dc.contributor.authorLaranjeira, Ronaldo Ramos [UNIFESP]
dc.contributor.authorBressan, Rodrigo A. [UNIFESP]
dc.contributor.authorLacerda, Acioly L. T. [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionJohns Hopkins Univ
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionInst Sinapse Neurociencias Clin
dc.contributor.institutionCtr Pesquisa & Ensaios Clin Sinapse Bairral
dc.date.accessioned2016-01-24T14:06:00Z
dc.date.available2016-01-24T14:06:00Z
dc.date.issued2011-01-01
dc.description.abstractBackground: Cannabis is the most used illicit drug in the world, and its use has been associated with prefrontal cortex (PFC) dysfunction, including deficits in executive functions (EF). Considering that EF may influence treatment outcome, it would be interesting to have a brief neuropsychological battery to assess EF in chronic cannabis users (CCU). in the present study, the Frontal Assessment Battery (FAB), a brief, easy to use neuropsychological instrument aimed to evaluate EF, was used to evaluate cognitive functioning of CCU. Methods: We evaluated 107 abstinent CCU with the FAB and compared with 44 controls matched for age, estimated IQ, and years of education. Results: CCU performed poorly as compared to controls (FAB total score = 16.53 vs. 17.09, p .05). CCU had also a poor performance in the Motor Programming subtest (2.47 vs. 2.73, p .05). Conclusion: This study examined effects of cannabis in executive functioning and showed evidence that the FAB is sensitive to detect EF deficits in early abstinent chronic cannabis users. Clinical significance of these findings remains to be investigated in further longitudinal studies. FAB may be useful as a screening instrument to evaluate the necessity for a complete neuropsychological assessment in this population.en
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Psiquiatria, LiNC, São Paulo, SP, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Psiquiatria, Unidade Pesquisas Alcool & Drogas UNIAD, São Paulo, SP, Brazil
dc.description.affiliationJohns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA
dc.description.affiliationUniv São Paulo, Fac Med, Dept Psiquiatria IPq, Programa Equilibrium, São Paulo, SP, Brazil
dc.description.affiliationInst Sinapse Neurociencias Clin, Campinas, SP, Brazil
dc.description.affiliationCtr Pesquisa & Ensaios Clin Sinapse Bairral, Itapira, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Psiquiatria, LiNC, São Paulo, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Psiquiatria, Unidade Pesquisas Alcool & Drogas UNIAD, São Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent523-531
dc.identifierhttp://dx.doi.org/10.1080/13803395.2010.535505
dc.identifier.citationJournal of Clinical and Experimental Neuropsychology. Philadelphia: Taylor & Francis Inc, v. 33, n. 5, p. 523-531, 2011.
dc.identifier.doi10.1080/13803395.2010.535505
dc.identifier.issn1380-3395
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/33311
dc.identifier.wosWOS:000291279800003
dc.language.isoeng
dc.publisherTaylor & Francis Inc
dc.relation.ispartofJournal of Clinical and Experimental Neuropsychology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.subjectPrefrontal cortexen
dc.subjectExecutive cognitive functionsen
dc.subjectCognitionen
dc.subjectCannabisen
dc.subjectMarijuanaen
dc.titleFrontal Assessment Battery (FAB) is a simple tool for detecting executive deficits in chronic cannabis usersen
dc.typeinfo:eu-repo/semantics/article
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