Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor

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dc.citation.volume8
dc.contributor.authorMathez, Andreia Latanza Gomes [UNIFESP]
dc.contributor.authorMoroto, Debora [UNIFESP]
dc.contributor.authorDib, Sergio Atala [UNIFESP]
dc.contributor.authorSa, Joao Roberto de [UNIFESP]
dc.coverageLondon
dc.date.accessioned2020-07-22T13:23:06Z
dc.date.available2020-07-22T13:23:06Z
dc.date.issued2016
dc.description.abstractA rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trelat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to non-islet cell tumor hypoglycemia. Doege-Potter syndrome is the name given to paraneoplastic hypoinsulinemic hypoglycemia in presence of a solitary fibrous tumor. This report describes a case of a patient with hypoinsulinemic hypoglycemia and Leser-Trelat sign associated with a malignant solitary fibrous tumor with IGF2 secretion. Both conditions have improved after tumor excision.en
dc.description.affiliationUniv Fed Sao Paulo, Div Endocrinol, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Div Endocrinol, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.1186/s13098-016-0148-2
dc.identifier.citationDiabetology & Metabolic Syndrome. London, v. 8, p. -, 2016.
dc.identifier.doi10.1186/s13098-016-0148-2
dc.identifier.fileWOS000375193500001.pdf
dc.identifier.issn1758-5996
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56033
dc.identifier.wosWOS:000375193500001
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofDiabetology & Metabolic Syndrome
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInsulin-like growth factor 2en
dc.subjectHypoglycemiaen
dc.subjectTumoren
dc.subjectSeborrheic keratosisen
dc.titleSeborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumoren
dc.typeinfo:eu-repo/semantics/article
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