Neurobehavioral profile of healthy full-term newborn infants of adolescent mothers

dc.contributor.authorBarros, Marina Carvalho de Moraes [UNIFESP]
dc.contributor.authorGuinsburg, Ruth [UNIFESP]
dc.contributor.authorMitsuhiro, Sandro [UNIFESP]
dc.contributor.authorChalem, Elisa [UNIFESP]
dc.contributor.authorLaranjeira, Ronaldo Ramos [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:49:48Z
dc.date.available2016-01-24T13:49:48Z
dc.date.issued2008-05-01
dc.description.abstractBackground: the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) is used to assess neurological integrity, behavioral function and the existence of stress and abstinence signs in newborn infants.Aim: To determine the neurobehavioral. profile of healthy term neonates of adolescent mothers.Design: Cross-sectional study with prospective collection of data.Subjects: 419 healthy newborns without analgesic/sedative use at labor, intra-uterine drug exposure, multiple gestation, congenital malformations or infections. the NNNS was applied with 33 7 hours of life in a quiet and dark room, between feedings. Outcome measures: Mean, SD, and 5th, 10th, 25th, 50th, 75th, 90th and 95th percentiles for each of 13 NNNS variables were determined and compared according to maternal age (12-14 years vs. 15-17 years vs. 18-19 years) by ANOVA.Results: Mothers had 17 +/- 1.5 years, 50% white, 7.1 +/- 2.2 years of education, prenatal care in 96%, vaginal delivery in 73%, and local/regional anesthesia in 75%. Neonates had birth weight 3205 299 g, gestational age 39.4 +/- 1.1 weeks, 55% male, 1 min Apgar 8.2 +/- 1.3, and 5 min Apgar 9.6 +/- 0.6. NNNS scores (mean +/- SD): habituation: 6.86 +/- 1.49; attention: 5.73 +/- 1.32; arousal: 3.70 +/- 0.70; regulation: 6.06 +/- 0.74; orientation handling procedures: 0.36 +/- 0.26; quality of movements: 5.11 +/- 0.49; excitability: 2.48 +/- 1.68; lethargy: 4.04 +/- 1.82; non-optimal reflexes: 3.67 +/- 1.35; asymmetry: 0.71 +/- 0.94; hypertonicity: 0.18 +/- 0.39; hypotonicity: 0.13 +/- 037; and stress/abstinence signs: 0.07 +/- 0.05. Infants of younger adolescent mothers were less lethargic than infants of older ones.Conclusion: the description of the neurobehavioral profile of healthy term newborns of adolescent mothers is important to establish normal standards for this population. (C) 2007 Elsevier Ireland Ltd. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Div Neonatal Med, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Res Unit Alcohol & Drugs, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Neonatal Med, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Res Unit Alcohol & Drugs, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent281-287
dc.identifierhttp://dx.doi.org/10.1016/j.earlhumdev.2007.07.001
dc.identifier.citationEarly Human Development. Clare: Elsevier B.V., v. 84, n. 5, p. 281-287, 2008.
dc.identifier.doi10.1016/j.earlhumdev.2007.07.001
dc.identifier.issn0378-3782
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30638
dc.identifier.wosWOS:000256536100001
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofEarly Human Development
dc.rightsAcesso restrito
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectbehavioren
dc.subjectpregnancy in adolescenceen
dc.subjectinfanten
dc.subjectnewbornen
dc.titleNeurobehavioral profile of healthy full-term newborn infants of adolescent mothersen
dc.typeArtigo
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