Chronic hepatosplenic schistosomiasis mansoni: magnetic resonance imaging and magnetic resonance angiography findings

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dc.contributor.authorBezerra, A. S. A.
dc.contributor.authorD'Ippolito, Giuseppe [UNIFESP]
dc.contributor.authorCaldana, R. P.
dc.contributor.authorCecin, A. O.
dc.contributor.authorAhmed, M.
dc.contributor.authorSzejnfeld, Jacob [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionBeth Israel Deaconess Med Ctr
dc.date.accessioned2016-01-24T12:41:57Z
dc.date.available2016-01-24T12:41:57Z
dc.date.issued2007-03-01
dc.description.abstractPurpose: To evaluate the hepatosplenic manifestations and the portal venous system in patients with chronic infection by Schistosoma mansoni.Material and Methods: A cross-sectional observational study was performed in 28 patients with chronic hepatosplenic schistosomiasis submitted to magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) of the abdomen. Images were interpreted independently by two radiologists to determine the reproducibility of image interpretation and who evaluated the presence of morphological alterations in the liver and spleen, such as hepatosplenomegaly, hepatic fissure widening, periportal fibrosis, and the presence of siderotic nodules. Interobserver and intra-observer agreement were measured with the kappa and intraclass correlation tests. Evaluation of venous collateral pathways and portal and splenic veins was done in consensus by both examiners.Results: Observers identified enlargement of the left lobe (78.5-92.8%) and caudate-to-right-lobe ratio (78.5-92.8%), irregularity of hepatic contours (89.2-96.4%), fissure widening (89.2-100%), and splenic siderotic nodules (84.2%). Splenomegaly, heterogeneity of hepatic parenchyma, peripheral hepatic vessels, and periportal fibrosis were observed in 100% of patients. MRI findings presented almost perfect interobserver (kappa = 0.65-1) and intra-observer (kappa = 0.73-1 for observer 1, and kappa = 0.65-1 for observer 2) agreement for the variables analyzed. MRA showed the presence of collateral pathways in the majority of patients (71.4%) along with widening of portal and splenic veins.Conclusion: Using MRI, hepatosplenic alterations in schistosomiasis are characterized by heterogeneity of hepatic parenchyma, presence of peripheral perihepatic vessels, periportal fibrosis, splenomegaly, siderotic nodules, and the presence of venous collateral pathways.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Diagnost Imaging, BR-04024002 São Paulo, Brazil
dc.description.affiliationBeth Israel Deaconess Med Ctr, Dept Radiol, Boston, MA 02215 USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Diagnost Imaging, BR-04024002 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent125-134
dc.identifierhttp://dx.doi.org/10.1080/02841850601105833
dc.identifier.citationActa Radiologica. Abingdon: Taylor & Francis Ltd, v. 48, n. 2, p. 125-134, 2007.
dc.identifier.doi10.1080/02841850601105833
dc.identifier.issn0284-1851
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29574
dc.identifier.wosWOS:000245792000003
dc.language.isoeng
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofActa Radiologica
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.subjectliveren
dc.subjectMR angiographyen
dc.subjectMR imagingen
dc.subjectparasitesen
dc.subjectspleenen
dc.titleChronic hepatosplenic schistosomiasis mansoni: magnetic resonance imaging and magnetic resonance angiography findingsen
dc.typeinfo:eu-repo/semantics/article
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