Increases in summer serum 25-hydroxyvitamin D (25OHD) concentrations in elderly subjects in São Paulo, Brazil vary with age, gender and ethnicity
dc.contributor.author | Maeda, Sergio Setsuo [UNIFESP] | |
dc.contributor.author | Kunii, Ilda Sizue [UNIFESP] | |
dc.contributor.author | Hayashi, Lilian Fukusima [UNIFESP] | |
dc.contributor.author | Lazaretti-Castro, Marise [UNIFESP] | |
dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
dc.date.accessioned | 2016-01-24T13:59:48Z | |
dc.date.available | 2016-01-24T13:59:48Z | |
dc.date.issued | 2010-06-14 | |
dc.description.abstract | Background: Hypovitaminosis D is a common condition among elderly individuals in temperate-climate countries, with a clear seasonal variation on 25 hydroxyvitamin D levels, increasing after summer and decreasing after winter, but there are few data from sunny countries such as Brazil. Many factors can interfere on vitamin D cutaneous synthesis. We aimed at studying the 25OHD variations during winter and summer in an outdoor physically active elderly population living in São Paulo city, and analysed their determining factors.Methods: Ninety-nine individuals (52 women and 47 men, from 55 to 83 years old) from different ethnic groups were selected from an outdoor physical activity group. Data are reported as Mean +/- SD, and we used Pearson Linear Correlation, Student's t-test for non-related samples, Chi-square (chi(2)) test and One-way ANOVA for analysis.Results: Mean 25OHD value for the whole group was 78.9 +/- 30.9 nmol/L in the winter and 91.6 +/- 31.7 nmol/L in the summer (p = 0.005). Mean winter serum 25OHD concentrations were not different between men and women (81.2 +/- 30.1 nmol/L vs. 76.7 +/- 31.8 nmol/L, respectively), and 19.2% of the individuals showed values < 50 nmol/L. in the summer, we noticed an increase only for men (107.6 +/- 31.4 nmol/L) compared to women (76.7 +/- 24.0 nmol/L), and 6.5% showed values < 50 nmol/L. A decrease in the mean PTH in the summer compared to the winter was noticed, with PTH levels showing a relationship with 25OHD concentrations only in the winter (r = -0.208, p = 0.041). White individuals showed an increase in mean serum 25OHD in the summer (p = 0.016) which was not noticed for other ethnic groups (Asians, native Brazilians and blacks). An increase in 25OHD values in the summer was observed in the age groups ranging from 51-60 and 61-70 years old (p < 0.05), but not in the age group from 71 years old on.Conclusions: 25OHD values increased during the summer in elderly residents of São Paulo, but to different extents depending on ethnicity, gender and age. This season-dependent increase was noticed only among men, white and who were in the youngest group of individuals. | en |
dc.description.affiliation | Universidade Federal de São Paulo UNIFESP, Dept Med, Div Endocrinol, EPM, São Paulo, Brazil | |
dc.description.affiliationUnifesp | Universidade Federal de São Paulo UNIFESP, Dept Med, Div Endocrinol, EPM, São Paulo, Brazil | |
dc.description.source | Web of Science | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.description.sponsorshipID | FAPESP: 03/13194-6 | |
dc.format.extent | 8 | |
dc.identifier | https://dx.doi.org/10.1186/1472-6823-10-12 | |
dc.identifier.citation | Bmc Endocrine Disorders. London: Biomed Central Ltd, v. 10, 8 p., 2010. | |
dc.identifier.doi | 10.1186/1472-6823-10-12 | |
dc.identifier.file | WOS000297286400001.pdf | |
dc.identifier.issn | 1472-6823 | |
dc.identifier.uri | https://repositorio.unifesp.br/handle/11600/32630 | |
dc.identifier.wos | WOS:000297286400001 | |
dc.language.iso | eng | |
dc.publisher | Biomed Central Ltd | |
dc.relation.ispartof | Bmc Endocrine Disorders | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.title | Increases in summer serum 25-hydroxyvitamin D (25OHD) concentrations in elderly subjects in São Paulo, Brazil vary with age, gender and ethnicity | en |
dc.type | info:eu-repo/semantics/article |
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