Chitosan in Nanostructured Thin Films

Página do item simplificado
dc.contributor.authorPavinatto, Felippe J.
dc.contributor.authorCaseli, Luciano [UNIFESP]
dc.contributor.authorOliveira, Osvaldo N.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:05:17Z
dc.date.available2016-01-24T14:05:17Z
dc.date.issued2010-08-01
dc.description.abstractThis review paper brings an overview of the use of chitosans in nanostructured films produced with the Langmuir-Blodgett (LB) or the electrostatic layer-by-layer (LbL) techniques, with emphasis on their possible applications. From a survey in the literature one may identify three main types of study with chitosan in nanostructured films. First, the interaction between chitosans and phospholipid Langmuir monolayers has been investigated for probing the mechanisms of chitosan action in their biological applications, with the monolayers serving as cell membrane models. in the second type, chitosan serves as a matrix for immobilization of biomolecules in LB as well as in LbL films, for which chitosan is suitable to help preserve the bioactivity of such biomolecules for long periods of time even in dry, solid films. An important application of these chitosan-containing films is in sensing and biosensing. the third type of study involves exploiting the mechanical and biocompatibility properties of chitosan in producing films with enhanced properties, for example, for tissue engineering. It is emphasized that chitosans have been proven excellent building blocks to produce films with controlled molecular architecture, allowing for synergy between distinct materials. We also discuss the prospects of the field, following a critical review of the latest developments in nanostructured chitosan films.en
dc.description.affiliationUniv São Paulo, Inst Fis Sao Carlos, Sao Carlos, SP, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Ciencias Exatas & Terra, Diadema, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Ciencias Exatas & Terra, Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent1897-1908
dc.identifierhttp://dx.doi.org/10.1021/bm1004838
dc.identifier.citationBiomacromolecules. Washington: Amer Chemical Soc, v. 11, n. 8, p. 1897-1908, 2010.
dc.identifier.doi10.1021/bm1004838
dc.identifier.issn1525-7797
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/32792
dc.identifier.wosWOS:000280583400001
dc.language.isoeng
dc.publisherAmer Chemical Soc
dc.relation.ispartofBiomacromolecules
dc.rightsAcesso restrito
dc.titleChitosan in Nanostructured Thin Filmsen
dc.typeResenha
Arquivos
Coleções
ICAQF - Outras produções