Raising the Bar(-seq) in Leishmania genetic screens
| dc.contributor.author | Ferreira, Tiago R. | |
| dc.contributor.author | Couñago, Rafael M. | |
| dc.contributor.author | Moretti, Nilmar Silvio [UNIFESP] | |
| dc.contributor.authorLattes | http://lattes.cnpq.br/2131472726202687 | pt_BR |
| dc.date.accessioned | 2021-11-29T15:57:30Z | |
| dc.date.available | 2021-11-29T15:57:30Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Our understanding of regulatory factors in Leishmania differentia- tion has long been restricted by the available genetic tools, but the availability of CRISPR/Cas9 has changed the landscape forever. Recently, Baker and Catta-Preta et al. applied Cas9 editing and kinome-wide bar-seq to dissect the function of 204 kinases in the Leishmania mexicana life cycle. | pt_BR |
| dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | pt_BR |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | pt_BR |
| dc.description.sponsorshipID | CNPq: 424729/2018 | pt_BR |
| dc.description.sponsorshipID | FAPESP: 2018/09948-0 | pt_BR |
| dc.identifier.doi | https://doi.org/10.1016/j.pt.2021.03.002 | pt_BR |
| dc.identifier.uri | https://hdl.handle.net/11600/62325 | |
| dc.language | eng | pt_BR |
| dc.publisher | Cell Press | pt_BR |
| dc.relation.ispartof | Trends in Parasitology | pt_BR |
| dc.rights | info:eu-repo/semantics/restrictedAccess | pt_BR |
| dc.subject | Leishmaniasis | pt_BR |
| dc.subject | Kinase | pt_BR |
| dc.subject | CRISPR-Cas9 | pt_BR |
| dc.title | Raising the Bar(-seq) in Leishmania genetic screens | pt_BR |
| dc.type | info:eu-repo/semantics/article | pt_BR |
| unifesp.campus | Escola Paulista de Medicina (EPM) | pt_BR |
| unifesp.departamento | Microbiologia, Imunologia e Parasitologia | pt_BR |
| unifesp.graduateProgram | Microbiologia e Imunologia | pt_BR |
| unifesp.knowledgeArea | Outra | pt_BR |