Anthocyanins as inflammatory modulators and the role of the gut microbiota

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dc.citation.volume33
dc.contributor.authorMorais, Carina Almeida [UNIFESP]
dc.contributor.authorDe Rosso, Veridiana Vera [UNIFESP]
dc.contributor.authorEstadella, Debora [UNIFESP]
dc.contributor.authorPisani, Luciana Pellegrini [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.coverageNew York
dc.date.accessioned2020-08-14T13:44:29Z
dc.date.available2020-08-14T13:44:29Z
dc.date.issued2016
dc.description.abstractThe health benefits of consuming fruits that are rich in polyphenols, especially anthocyanins, have been the focus of recent in vitro and in vivo investigations. Thus, greater attention is being directed to the reduction of the inflammatory process associated with the intestinal microbiota and the mechanism underlying these effects because the microbiota has been closely associated with the metabolism of these compounds in the gastrointestinal tract. Further interest lies in the ability of these metabolites to modulate the growth of specific intestinal bacteria. Thus, this review examines studies involving the action of the anthocyanins that are present in many fruits and their effect in the modulating the inflammatory process associated with the interaction between the host and the gut microbiota. The findings of both in vitro and in vivo studies suggest a potential antiinflammatory effect of these compounds, which seem to inhibit activation of the signaling pathway mediated by the transcription factor NF kappa B. This effect is associated with modulation of a beneficial gut microbiota, particularly an increase in Bifidobacterium strains. (C) 2015 Elsevier Inc. All rights reserved.en
dc.description.affiliationUniv Fed Sao Paulo, Inst Saude & Soc, Dept Biociencias, Santos, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Inst Saude & Soc, Dept Biociencias, Santos, SP, Brazil
dc.description.provenanceMade available in DSpace on 2020-08-14T13:44:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2016en
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt
dc.description.sponsorshipIDFAPESP: 2013/25101-4pt
dc.format.extent1-7
dc.identifierhttps://dx.doi.org/10.1016/j.jnutbio.2015.11.008
dc.identifier.citationJournal Of Nutritional Biochemistry. New York, v. 33, p. 1-7, 2016.
dc.identifier.doi10.1016/j.jnutbio.2015.11.008
dc.identifier.issn0955-2863
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57701
dc.identifier.wosWOS:000378011400001
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofJournal Of Nutritional Biochemistry
dc.rightsAcesso restrito
dc.subjectAnthocyaninen
dc.subjectInflammationen
dc.subjectNF kappa Ben
dc.subjectMicrobiotaen
dc.subjectBifidobacteriumen
dc.titleAnthocyanins as inflammatory modulators and the role of the gut microbiotaen
dc.typeArtigo
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