Food Intake, Growth and Body Composition of Children and Adolescents With Autoimmune Hepatitis
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2010-03-01
Autores
Bidutte Cortez, Ana Paula 
Morais, Mauro Batista de
Speridião, Patrícia da Graça Leite
Guedes da Motta Mattar, Regina Helena
Calanca, Flavia
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Objective: To evaluate the food intake, anthropometry, body composition, and sexual maturity of children and adolescents with autoimmune hepatitis.Methods: Thirty-seven children and adolescents with autoimmune hepatitis were studied. A questionnaire was given to evaluate food intake over a 24-hour period. Weight, height, and skin-fold thickness were measured. Electric impedance and skin-fold using Slaughter formula were used to evaluate body composition. Sexual maturity was evaluated using the Tanner stage method. Cumulative intake of corticosteroids was determined based on medical records.Results: Most of the subjects were females (83.3%). Food intake did not meet recommended dietary intakes for energy, calcium, and vitamin A for 43.2%, 94.6%, and 59.4% of the patients, respectively. All subjects were in their respective pubertal developmental stage. A lower Z score for height-for-age (< -2.0 standard deviation) was found in 3/37 (10.5%) of the patients. Body fat over 30% was found in female patients by bioimpedance (41.9%) and skin-fold (45.2%) evaluation. There was a positive correlation between the 2 methods of measuring body fat (r = +0.800; P < 0.001). A larger reduction (P < 0.005) in Z score for height-for-age was observed in patients that received a cumulative dose of corticosteroids of more than 10.0 g.Conclusions: Food intake in children and adolescents with autoimmune hepatitis is below recommended standards especially for energy, calcium, and vitamin A. Cumulative dose of corticoids was associated with reduction of Z score for height-for-age.
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Journal of Clinical Gastroenterology. Philadelphia: Lippincott Williams & Wilkins, v. 44, n. 3, p. 200-207, 2010.