A 4-Year Prospective Urological Assessment of In Utero Myelomeningocele Repair-Does Gestational Age at Birth Have a Role in Later Neurogenic Bladder Pattern?

Página do item simplificado
dc.citation.issue6
dc.citation.volume197
dc.contributor.authorda Cruz, Marcela Leal [UNIFESP]
dc.contributor.authorLiguori, Riberto [UNIFESP]
dc.contributor.authorGarrone, Gilmar [UNIFESP]
dc.contributor.authorOttoni, Sergio Leite [UNIFESP]
dc.contributor.authorCavalheiro, Sergio [UNIFESP]
dc.contributor.authorMoron, Antonio Fernandes [UNIFESP]
dc.contributor.authorMacedo, Antonio, Jr. [UNIFESP]
dc.coverageNew York
dc.date.accessioned2020-07-13T11:53:11Z
dc.date.available2020-07-13T11:53:11Z
dc.date.issued2017
dc.description.abstractPurpose: Premature delivery is a major complication of in utero myelomeningocele repair. The prematurity rate in MOMS (Management of Myelomeningocele Study) was 79%, with a mean gestational age at birth of 34 weeks. We speculated that prematurity could also influence urological outcome in patients operated on prenatally for myelomeningocele. Materials and Methods: Beginning in November 2011, we prospectively followed a population of patients with myelomeningocele who had undergone in utero repair. Results: We compared patients based on gestational age at birth, ie younger than 34 weeks (group 1, 42 patients) and 34 weeks or older (group 2, 37 patients). Mean gestational age at birth was 28.3 weeks (range 25 to 33) in group 1 and 35.2 weeks (34 to 38) in group 2. Of the cases 47.5% in group 1 were classified as high risk, 35% as incontinent, 10% as hypocontractile and 7.5% as normal. By comparison, 54.5% of cases in group 2 were classified as high risk, 33.3% as incontinent and 12.1% as normal. Differences between the groups were not statistically significant. Mean followup was 27.9 months in group 1 and 24.3 months in group 2. Conclusions: Our results show that gestational age at birth has little impact on bladder pattern. These data reinforce the need to follow this population closely.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Urol, Div Pediat Urol, Ctr Supporting Children Urol Anomalies, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Neurosurg, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Obstet Fetal Med, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Pediat, Sao Paulo, Brazil
dc.description.affiliationSanta Joana Matern Hosp, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Urol, Div Pediat Urol, Ctr Supporting Children Urol Anomalies, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Neurosurg, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Obstet Fetal Med, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Pediat, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1550-1554
dc.identifierhttp://dx.doi.org/10.1016/j.juro.2016.12.014
dc.identifier.citationJournal Of Urology. New York, v. 197, n. 6, p. 1550-1554, 2017.
dc.identifier.doi10.1016/j.juro.2016.12.014
dc.identifier.issn0022-5347
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54435
dc.identifier.wosWOS:000400896400083
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofJournal Of Urology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectmeningomyeloceleen
dc.subjectfetal therapiesen
dc.subjecturodynamicsen
dc.subjectprenatal diagnosisen
dc.titleA 4-Year Prospective Urological Assessment of In Utero Myelomeningocele Repair-Does Gestational Age at Birth Have a Role in Later Neurogenic Bladder Pattern?en
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos