Intestinal metaplasia in gallbladders: prevalence study

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dc.contributor.authorFernandes, Jose Eduardo Vasconcelos
dc.contributor.authorFranco, Maria Isete Fares
dc.contributor.authorSuzuki, Reinaldo Kenji
dc.contributor.authorTavares, Nelson Mattos
dc.contributor.authorBromberg, Sansom Henrique [UNIFESP]
dc.contributor.institutionHosp Serv Publ Estadual Sao Paulo
dc.contributor.institutionUniv Metropolitana Santos
dc.contributor.institutionUniversidade de SĂŁo Paulo (USP)
dc.contributor.institutionUniv Lusiada
dc.contributor.institutionSanta Casa Misericordia Santos
dc.contributor.institutionUniversidade Federal de SĂŁo Paulo (UNIFESP)
dc.date.accessioned2018-06-18T11:54:44Z
dc.date.available2018-06-18T11:54:44Z
dc.date.issued2008-07-03
dc.description.abstractCONTEXT AND OBJECTIVE: Gallbladder cancer is usually diagnosed at a late stage and generally results in death. Discovery of predisposing factors for this neoplasia could prevent this outcome. In this study, we assess the presence of one of these factors: intestinal metaplasia in gallbladders with stones and inflammatory processes.DESIGN AND SETTING: Cross-sectional study in Hospital do Servidor Publico Estadual de Sao Paulo.METHOD: The first 80 gallbladders from patients who underwent elective cholecystectomy between April and August 2002, presenting stones and chronic inflammation, were studied. The patients were divided into groups according to their age: CC 1, from 15 to 40 years; CC2, from A I to 60 years; and CC3, from 61 to 85 years.RESULTS: Twenty-one patients (26%) were male, while 59 (74%) were female. In the group CC 1, intestinal metaplasia was present in 85.71% of the 21 patients studied; in CC2, in 79.41% of 34 patients; and in CC3, in 56.00% of 25 patients. These differences presented statistical significance (p = 0.04542).CONCLUSION: Intestinal metaplasia is extremely frequent in gallbladders with inflammation and lithiasis, especially in younger patients.en
dc.description.affiliationHosp Serv Publ Estadual Sao Paulo, Dept Surg Gastroenterol, Postgrad Program Surg Gastroenterol, Sao Paulo, Brazil
dc.description.affiliationUniv Metropolitana Santos, Sch Hlth Sci, Dept Gastroenterol, Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Sch Dent, Dept Stomatol & Clin Pathol, Sao Paulo, Brazil
dc.description.affiliationUniv Lusiada, Sch Hlth Sci, Dept Gastroenterol, Sao Paulo, Brazil
dc.description.affiliationSanta Casa Misericordia Santos, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Discipline Expt Surg, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Discipline Expt Surg, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent220-222
dc.identifierhttp://dx.doi.org/10.1590/S1516-31802008000400004
dc.identifier.citationSao Paulo Medical Journal. Sao Paulo: Associacao Paulista Medicina, v. 126, n. 4, p. 220-222, 2008.
dc.identifier.doi10.1590/S1516-31802008000400004
dc.identifier.fileS1516-31802008000400004.pdf
dc.identifier.issn1516-3180
dc.identifier.scieloS1516-31802008000400004
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/45542
dc.identifier.wosWOS:000260203000004
dc.language.isoeng
dc.publisherAssociacao Paulista Medicina
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLithiasisen
dc.subjectCholecystitisen
dc.subjectGallbladderen
dc.subjectMetaplasiaen
dc.subjectCholecystectomyen
dc.titleIntestinal metaplasia in gallbladders: prevalence studyen
dc.title.alternativeMetaplasia intestinal na vesĂ­cula biliar: estudo da prevalĂȘnciapt
dc.typeinfo:eu-repo/semantics/article
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