Can breast tumors affect the oxidative status of the surrounding environment? A comparative analysis among cancerous breast, mammary adjacent tissue, and plasma

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dc.contributor.authorPanis, C.
dc.contributor.authorVictorino, V. J.
dc.contributor.authorHerrera, A. C. S. A.
dc.contributor.authorCecchini, A. L.
dc.contributor.authorSimao, A. N. C.
dc.contributor.authorTomita, L. Y. [UNIFESP]
dc.contributor.authorCecchini, R.
dc.date.accessioned2019-01-21T10:30:06Z
dc.date.available2019-01-21T10:30:06Z
dc.date.issued2016
dc.description.abstractIn this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.en
dc.description.affiliationLaboratory of Inflammatory Mediators, State University of West Paraná (UNIOESTE), Campus Francisco Beltrão, 85605-010 Francisco Beltrão, PR, Brazil
dc.description.affiliationSchool of Medicine, State University of Sao Paulo (USP), 07112-000 Sao Paulo, SP, Brazil
dc.description.affiliationSchool of Medicine, Pontifícia Universidade Católica (PUC), Campus Londrina, 86051-990 Londrina, PR, Brazil
dc.description.affiliationLaboratory of Physiopathology and Free Radicals, Department of General Pathology, State University of Londrina (UEL), 86051-990 Londrina, PR, Brazil
dc.description.affiliationUniversity Hospital, Department of Pharmacy, State University of Londrina (UEL), 86051-990 Londrina, PR, Brazil
dc.description.affiliationDepartment of Preventive Medicine, Federal University of São Paulo (UNIFESP), 07112-000 São Paulo, SP, Brazil
dc.description.affiliationUnifespDepartment of Preventive Medicine, Federal University of São Paulo (UNIFESP), 07112-000 São Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCAPES
dc.description.sponsorshipCNPq
dc.description.sponsorshipFundacao Araucaria
dc.identifierhttp://dx.doi.org/10.1155/2016/6429812
dc.identifier.citationOxidative Medicine And Cellular Longevity. London, 2016.
dc.identifier.doi10.1155/2016/6429812
dc.identifier.fileWOS000372235600001.pdf
dc.identifier.issn1942-0900
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/49582
dc.identifier.wosWOS:000372235600001
dc.language.isoeng
dc.publisherHindawi ltd
dc.relation.ispartofOxidative Medicine And Cellular Longevity
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNipple Aspirate Fluidsen
dc.subjectLipid-Peroxidationen
dc.subjectStressen
dc.subjectMicroenvironmenten
dc.subjectWomenen
dc.subjectProteinsen
dc.subjectProgressionen
dc.subjectEstrogenen
dc.subjectProfileen
dc.subjectMarkeren
dc.titleCan breast tumors affect the oxidative status of the surrounding environment? A comparative analysis among cancerous breast, mammary adjacent tissue, and plasmaen
dc.typeinfo:eu-repo/semantics/article
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