Costs of hospitalization in preterm infants: impact of antenatal steroid therapy

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dc.contributor.authorOgata, Joice Fabiola Meneguel [UNIFESP
dc.contributor.authorFonseca, Marcelo Cunio Machado [UNIFESP]
dc.contributor.authorMiyoshi, Milton Harumi [UNIFESP]
dc.contributor.authorAlmeida, Maria Fernanda Branco de [UNIFESP]
dc.contributor.authorGuinsburg, Ruth [UNIFESP]
dc.date.accessioned2019-01-21T10:30:07Z
dc.date.available2019-01-21T10:30:07Z
dc.date.issued2016
dc.description.abstractObjective: To estimate the costs of hospitalization in premature infants exposed or not to antenatal corticosteroids (ACS). Method: Retrospective cohort analysis of premature infants with gestational age of 26-32 weeks without congenital malformations, born between January of 2006 and December of 2009 in a tertiary, public university hospital. Maternal and neonatal demographic data, neonatal morbidities, and hospital inpatient services during the hospitalization were collected. The costs were analyzed using the microcosting technique. Results: Of 220 patients that met the inclusion criteria, 211 (96%) charts were reviewed: 170 newborns received at least one dose of antenatal corticosteroid and 41 did not receive the antenatal medication. There was a 14-37% reduction of the different cost components in infants exposed to ACS when the entire population was analyzed, without statistical significance. Regarding premature infants who were discharged alive, there was a 24-47% reduction of the components of the hospital services costs for the ACS group, with a significant decrease in the length of stay in the neonatal intensive care unit (NICU). In very-low birth weight infants, considering only the survivors, ACS promoted a 30-50% reduction of all elements of the costs, with a 36% decrease in the total cost (p = 0.008). The survivors with gestational age < 30 weeks showed a decrease in the total cost of 38% (p = 0.008) and a 49% reduction of NICU length of stay (p = 0.011). Conclusion: ACS reduces the costs of hospitalization of premature infants who are discharged alive, especially those with very low birth weight and < 30 weeks of gestational age. (C) 2015 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.en
dc.description.affiliationDisciplina de Pediatria Neonatal, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
dc.description.affiliationDisciplina de Ginecologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
dc.description.affiliationUnifespDisciplina de Pediatria Neonatal, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
dc.description.affiliationUnifespDisciplina de Ginecologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
dc.description.sourceWeb of Science
dc.format.extent24-31
dc.identifierhttp://dx.doi.org/10.1016/j.jped.2015.03.004
dc.identifier.citationJornal De Pediatria. Rio de janeiro, rj, v. 92, n. 1, p. 24-31, 2016.
dc.identifier.doi10.1016/j.jped.2015.03.004
dc.identifier.fileS0021-75572016000100024.pdf
dc.identifier.issn0021-7557
dc.identifier.scieloS0021-75572016000100024
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/49593
dc.identifier.wosWOS:000371471300005
dc.language.isoeng
dc.publisherSoc brasil pediatria
dc.relation.ispartofJornal De Pediatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPreterm Infanten
dc.subjectCosts And Cost Analysisen
dc.subjectHospitalizationen
dc.subjectGlucocorticoidsRespiratory-Distress-Syndromeen
dc.subjectBirthen
dc.subjectPreventionen
dc.subjectMortalityen
dc.subjectSurvivalen
dc.subjectDeathsen
dc.subjectRisken
dc.titleCosts of hospitalization in preterm infants: impact of antenatal steroid therapyen
dc.titleCustos da hospitalização de recém-nascidos pré-termo: impacto da corticoterapia antenatalpt
dc.typeinfo:eu-repo/semantics/article
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