Air pollution and its relationship to lung function among adolescents from Taubate, Sao Paulo, Brazil

Página do item simplificado
dc.citation.issue2
dc.citation.volumev. 46
dc.contributor.authorToledo, M. Froio
dc.contributor.authorSaraiva-Romanholo, B. Mangueira
dc.contributor.authorOliveira, R. Carvalho
dc.contributor.authorSilva, L. Ferraz da
dc.contributor.authorSolé, Dirceu [UNIFESP]
dc.coverageBarcelona
dc.date.accessioned2020-07-20T16:31:22Z
dc.date.available2020-07-20T16:31:22Z
dc.date.issued2018
dc.description.abstractBackground: This paper sought to evaluate individual exposure to air pollution by quantifying the carbon in alveolar macrophages (AMs) and its relationship to lung function. We also examined the proximity of participants' residences to the Presidente Dutra highway (PDH) in adolescents with asthma from Taubate, Sao Paulo, Brazil. Methods: This descriptive study examined fifty 13- to 14-year-old adolescents with asthma identified by the International Study of Asthma and Allergies in Childhood (ISAAC) in Taubate. These adolescents underwent spirometry and sputum induction via the inhalation of 3% hypertonic saline (HSS). Sputum was collected after each nebulisation, and forced expiratory flow in one second (FEV1) was measured. The collected sputum was stored and transported to the laboratoryen
dc.description.abstractit was then processed and analysed for ultrafine particles (<100 nm). This analysis was correlated with the residence location and FEVi of each adolescent. Results: A total of 39 adolescents completed the study. The comparison of the carbon fraction within macrophages (CA/MA) showed no differences according to residence in relation to the PDH (p = 0.758). After adjustment, a mixed linear model with FEV1 as the dependent variable and CA/MA, location, and evaluation condition as the predictors found that the interactions among the variables were not significant. Conclusions: The amount of carbon present within the AMs of adolescents with asthma was not correlated with either lung function or residence location. Evaluations of the topography and local climatic conditions in Taubate should be considered in future studies. (C) 2017 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.en
dc.description.affiliationUniv Taubate UNITAU, Dept Med, Taubate, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Dept Med, Expt Therapeut Lab 1, LIM 20, Sao Paulo, Brazil
dc.description.affiliationUniv City Sao Paulo UNICID, Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Med Sch, Dept Pathol, Expt Air Pollut Lab, Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Sch Med, Dept Pathol, Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Sao Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent160-166
dc.identifierhttp://dx.doi.org/10.1016/j.aller.2017.04.007
dc.identifier.citationAllergologia Et Immunopathologia. Barcelona, v. 46, n. 2, p. 160-166, 2018.
dc.identifier.doi10.1016/j.aller.2017.04.007
dc.identifier.issn0301-0546
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55923
dc.identifier.wosWOS:000426799400010
dc.language.isoeng
dc.publisherElsevier Doyma Sl
dc.relation.ispartofAllergologia Et Immunopathologia
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAsthmaen
dc.subjectAdolescenten
dc.subjectPollutionen
dc.subjectSooten
dc.subjectLung functionen
dc.subjectResidenceen
dc.subjectHighwayen
dc.titleAir pollution and its relationship to lung function among adolescents from Taubate, Sao Paulo, Brazilen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos