The relevance of performing exercise test before starting supervised physical exercise in asymptomatic cardiovascular patients with rheumatic diseases

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dc.citation.issue11
dc.citation.volume55
dc.contributor.authorKlemz, Barbara Nascimento de Carvalho [UNIFESP]
dc.contributor.authorReis-Neto, Edgard Torres dos [UNIFESP]
dc.contributor.authorJennings, Fabio [UNIFESP]
dc.contributor.authorSiqueira, Usmary Sardinha [UNIFESP]
dc.contributor.authorKlemz, Fabio Kadratz
dc.contributor.authorCosta Pinheiro, Helder Henrique
dc.contributor.authorSato, Emilia Inoue [UNIFESP]
dc.contributor.authorNatour, Jamil [UNIFESP]
dc.contributor.authorSzejnfeld, Vera Lucia [UNIFESP]
dc.contributor.authorPinheiro, Marcelo de Medeiros [UNIFESP]
dc.coverageOxford
dc.date.accessioned2020-07-31T12:47:25Z
dc.date.available2020-07-31T12:47:25Z
dc.date.issued2016
dc.description.abstractObjectives. To evaluate the impact and risk factors associated with an abnormal exercise test ( ET) in systemic inflammatory rheumatic disease ( SIRD) patients before commencing supervised physical exercise. Methods. A total of 235 SIRD patients were enrolled in three controlled clinical trials, including 103 RA, 42 SLE and 57 AS patients. The control group consisted of 231 healthy, sedentary subjects matched for age, gender and BMI. All performed an ET, according to Bruce's or Ellestad's protocol. Cardiovascular disease risk factors, medications, comorbidities and details of each SIRD were assessed. Results. SIRD patients had a higher percentage of abnormal ETs compared with the control group, especially exercise hypertensive behaviour, higher oxygen consumption, higher resting heart rate and heart rate at the first minute of recovery, and chronotropic incompetence (C-Inc) (P < 0.001). The disease itself was involved with higher likelihood of having an abnormal ET [Odds ratio (OR) = 12.0, 95% CI: 2.5, 56.7en
dc.description.abstractP = 0.002 for SLEen
dc.description.abstractOR = 13.56, 95% CI: 6.16, 29.8en
dc.description.abstractP < 0.001 for RAen
dc.description.abstractand OR = 4.31, 95% CI: 1.17, 15.8en
dc.description.abstractP = 0.028, for AS]. Each 10-year increment of age increased the chance of having an abnormal ET by 13% (P = 0.008) in AS patients, as well as hypertension (OR = 7.14, 95% CI: 1.61, 31.6en
dc.description.abstractP = 0.01). Regarding C-Inc, age played a protective role (OR = 0.88, 95% CI: 0.78, 0.99en
dc.description.abstractP = 0.043) in SLE, and ASDAS-ESR was associated with a higher risk in AS (OR = 2.73, 95% CI: 0.93, 8.0en
dc.description.abstractP = 0.067). Conclusion. Our results showed a higher prevalence of abnormal ETs in asymptomatic cardiovascular SIRD patients, and the disease itself was associated with a higher likelihood of having an abnormal test, emphasizing the relevance and need of performing it before starting supervised physical exercise.en
dc.description.affiliationFed Univ Sao Paulo UNIFESP EPM, Div Rheumatol, Sao Paulo, Brazil
dc.description.affiliationDante Pazzanese Hosp, Dept Cardiol, Sao Paulo, Brazil
dc.description.affiliationFed Univ Para UFPA, Sch Dent, Para, Brazil
dc.description.affiliationUnifespRheumatology Division, Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), São Paulo, Brasil
dc.description.sourceWeb of Science
dc.format.extent1978-1986
dc.identifierhttp://dx.doi.org/10.1093/rheumatology/kew277
dc.identifier.citationRheumatology. Oxford, v. 55, n. 11, p. 1978-1986, 2016.
dc.identifier.doi10.1093/rheumatology/kew277
dc.identifier.issn1462-0324
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56824
dc.identifier.wosWOS:000388555100010
dc.language.isoeng
dc.publisherOxford Univ Press
dc.relation.ispartofRheumatology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectrheumatoid arthritisen
dc.subjectsystemic lupus erythematosusen
dc.subjectankylosing spondylitisen
dc.subjectexerciseen
dc.subjectcardiovascularen
dc.titleThe relevance of performing exercise test before starting supervised physical exercise in asymptomatic cardiovascular patients with rheumatic diseasesen
dc.typeinfo:eu-repo/semantics/article
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