Treating drug dependence with the aid of ibogaine: A retrospective study

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dc.contributor.authorSchenberg, Eduardo Ekman [UNIFESP]
dc.contributor.authorComis, Maria Angélica de Castro [UNIFESP]
dc.contributor.authorChaves, Bruno Rasmussen
dc.contributor.authorSilveira, Dartiu Xavier da [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionInst Plantando Consciencia
dc.contributor.institutionMPPG Hosp
dc.date.accessioned2016-01-24T14:38:09Z
dc.date.available2016-01-24T14:38:09Z
dc.date.issued2014-11-01
dc.description.abstractIbogaine is an alkaloid purported to be an effective drug dependence treatment. However, its efficacy has been hard to evaluate, partly because it is illegal in some countries. in such places, treatments are conducted in underground settings where fatalities have occurred. in Brazil ibogaine is unregulated and a combined approach of psychotherapy and ibogaine is being practiced to treat addiction. To evaluate the safety and efficacy of ibogaine, we conducted a retrospective analysis of data from 75 previous alcohol, cannabis, cocaine and crack users (72% poly-drug users). We observed no serious adverse reactions or fatalities, and found 61% of participants abstinent. Participants treated with ibogaine only once reported abstinence for a median of 5.5 months and those treated multiple times for a median of 8.4 months. This increase was statistically significant (p < 0.001), and both single or multiple treatments led to longer abstinence periods than before the first ibogaine session (p < 0.001). These results suggest that the use of ibogaine supervised by a physician and accompanied by psychotherapy can facilitate prolonged periods of abstinence, without the occurrence of fatalities or complications. These results suggest that ibogaine can be a safe and effective treatment for dependence on stimulant and other non-opiate drugs.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psiquiatria, Inst Plantando Consciencia, BR-04002030 São Paulo, Brazil
dc.description.affiliationInst Plantando Consciencia, BR-04002030 São Paulo, Brazil
dc.description.affiliationMPPG Hosp, Santa Cruz Do Rio Pardo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psiquiatria, Inst Plantando Consciencia, Programa Orientacao & Atendimento Dependentes PRO, BR-04002030 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psiquiatria, Inst Plantando Consciencia, BR-04002030 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psiquiatria, Inst Plantando Consciencia, Programa Orientacao & Atendimento Dependentes PRO, BR-04002030 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipInstituto Plantando Consciencia, a Brazilian non-profit organization
dc.format.extent993-1000
dc.identifierhttp://dx.doi.org/10.1177/0269881114552713
dc.identifier.citationJournal of Psychopharmacology. London: Sage Publications Ltd, v. 28, n. 11, p. 993-1000, 2014.
dc.identifier.doi10.1177/0269881114552713
dc.identifier.issn0269-8811
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/38433
dc.identifier.wosWOS:000343976600003
dc.language.isoeng
dc.publisherSage Publications Ltd
dc.relation.ispartofJournal of Psychopharmacology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.uk.sagepub.com/aboutus/openaccess.htm
dc.subjectIbogaineen
dc.subjectdependenceen
dc.subjectaddictionen
dc.subjectcocaineen
dc.subjectcracken
dc.titleTreating drug dependence with the aid of ibogaine: A retrospective studyen
dc.typeinfo:eu-repo/semantics/article
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