Trabeculectomy with mitomycin C in glaucoma associated with uveitis

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dc.contributor.authorPrata Junior, João Antonio [UNIFESP]
dc.contributor.authorNeves, Renato Augusto [UNIFESP]
dc.contributor.authorMinckler, Donald S.
dc.contributor.authorMermoud, André
dc.contributor.authorHeuer, Dale K.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUNIV CAPE TOWN
dc.date.accessioned2018-06-18T11:23:32Z
dc.date.available2018-06-18T11:23:32Z
dc.date.issued1994-09-01
dc.description.abstractTwenty-four trabeculectomies performed in 24 patients for control of uveitic galucoma were retrospectively evaluated to analyze the effect of intraoperative application of mitomycin C (MMC) on the short-term outcome of trabeculectomy for glaucoma associated with uveitis. Success rates, postoperative levels of intraocular pressure (IOP), and complications were studied. After a mean follow up of 9.87 months (range, 3 to 27 months), 18 eyes (75%) achieved an IOP of 21 mm Hg or less without antiglaucoma medications. The same IOP levels with one antiglaucoma medication was achieved in four eyes (16.6%). Statistical analysis demonstrated a significant reduction in IOP postoperatively during the period studied (P = .0001). Complications observed included exacerbation of the uveitis (12.5%), choroidal detachment (12.5%), hypotony (8.3%), postoperative shallow anterior chamber (4.2%), wound leak (4.2%), hyphema (4.2%), and macular edema (4.2%). The results of this retrospective and uncontrolled study suggest that intraoperative application of MMC may be a good option for enhancement of short-term trabeculectomy success rates in cases of uveitic glaucoma.en
dc.description.affiliationESCOLA PAULISTA MED,DEPT OPHTHALMOL,BR-04023 SAO PAULO,BRAZIL
dc.description.affiliationUNIV CAPE TOWN,DEPT OPHTHALMOL,CAPE TOWN,SOUTH AFRICA
dc.description.affiliationUnifespESCOLA PAULISTA MED,DEPT OPHTHALMOL,BR-04023 SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent616-620
dc.identifierhttp://dx.doi.org/10.3928/1542-8877-19940901-28
dc.identifier.citationOphthalmic Surgery And Lasers. Thorofare: Slack Inc, v. 25, n. 9, p. 616-620, 1994.
dc.identifier.doi10.3928/1542-8877-19940901-28
dc.identifier.issn0022-023X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/45068
dc.identifier.wosWOS:A1994PN74900013
dc.language.isoeng
dc.publisherSlack Inc
dc.relation.ispartofOphthalmic Surgery And Lasers
dc.rightsAcesso restrito
dc.titleTrabeculectomy with mitomycin C in glaucoma associated with uveitisen
dc.typeArtigo
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