Vasoplegic syndrome after off-pump coronary artery bypass surgery

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dc.contributor.authorGomes, Walter José [UNIFESP]
dc.contributor.authorErlichman, Manes R. [UNIFESP]
dc.contributor.authorBatista, Mario L.
dc.contributor.authorKnobel, Marcos
dc.contributor.authorAlmeida, Dirceu Rodrigues de [UNIFESP]
dc.contributor.authorCarvalho, Antonio Carlos [UNIFESP]
dc.contributor.authorCatani, Roberto [UNIFESP]
dc.contributor.authorBuffolo, Enio [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:33:41Z
dc.date.available2016-01-24T12:33:41Z
dc.date.issued2003-02-01
dc.description.abstractObjective: the vasoplegic syndrome (VS) has been implicated in life-threatening complications after open heart surgery, where the whole-body inflammatory reaction is attributed to the cardiopulmonary bypass (CPB). Off-pump coronary artery bypass grafting (OPCAB) has been recently achieving growing enthusiasm mainly due avoiding the side effects of CPB. However herein the occurrence of VS in OPCAB is reported. Methods: the vasoplegic syndrome usual findings occurring in the early postoperative period include severe hypotension, tachycardia, normal or elevated cardiac output and low systemic vascular resistance. Four patients underwent to OPCAB presented all the signs of VS intraoperatively or within the first 6 postoperative h. Results: the patients needed aggressive vasoactive drug support for hemodynamic stabilization and all of them developed complications. These patients also had tendency to require administration of blood and blood derivatives due to diffuse and oozing type bleeding. Mean intensive care unit stay of surviving patients was 70 h and mean period of postoperative hospitalization was 9 days. Tumor necrosis factor-ot blood levels in one patient were elevated postoperatively though no signs of infection were observed. One patient died. Conclusions: Although vasoplegic syndrome can complicate OPCAB surgery, the rationale for avoiding CPB remains valid considering the benefits provided by OPCAB. (C) 2002 Elsevier Science B.V. All fights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Cardiovasc Surg Discipline, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, São Paulo Hosp, BR-04023900 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Cardiovasc Surg Discipline, BR-04023900 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, São Paulo Hosp, BR-04023900 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent165-169
dc.identifierhttps://dx.doi.org/10.1016/S1010-7940(02)00734-0
dc.identifier.citationEuropean Journal of Cardio-thoracic Surgery. Amsterdam: Elsevier B.V., v. 23, n. 2, p. 165-169, 2003.
dc.identifier.doi10.1016/S1010-7940(02)00734-0
dc.identifier.issn1010-7940
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/27120
dc.identifier.wosWOS:000180995200007
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofEuropean Journal of Cardio-thoracic Surgery
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectHeart surgeryen
dc.subjectCoronary artery bypass surgeryen
dc.subjectVasoplegiaen
dc.subjectSystemic inflammatory response syndromeen
dc.titleVasoplegic syndrome after off-pump coronary artery bypass surgeryen
dc.typeinfo:eu-repo/semantics/article
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