Ethnic disparity in spontaneous preterm birth and maternal pre-pregnancy body mass index

Página do item simplificado
dc.contributor.authorTorloni, Maria Regina [UNIFESP]
dc.contributor.authorFortunato, Stephen J.
dc.contributor.authorBetran, Ana Pilar
dc.contributor.authorWilliams, Scott
dc.contributor.authorBrou, Lina
dc.contributor.authorDrobek, Cayce Owens
dc.contributor.authorMerialdi, Mario
dc.contributor.authorMenon, Ramkumar
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionCentennial Womens Hosp
dc.contributor.institutionWorld Hlth Org
dc.contributor.institutionVanderbilt Univ
dc.contributor.institutionEmory Univ
dc.contributor.institutionUniv Texas Med Branch Galveston
dc.date.accessioned2016-01-24T14:27:03Z
dc.date.available2016-01-24T14:27:03Z
dc.date.issued2012-04-01
dc.description.abstractTo investigate differences in pre-pregnancy BMI status in patients with spontaneous preterm birth (PTB) compared with term birth and assess the role of ethnicity as a risk modifier in BMI-associated PTB.A case-control study involving self-reported African American and Caucasian women delivering singletons in Nashville, TN, USA, 2003-2009. Maternal pre-pregnancy BMI was recorded in 447 PTB-cases (African American = 145, Caucasian = 302) and 1315 term-birth controls (African American = 522; Caucasian = 793). Crude and adjusted odds ratio (OR and AOR) for PTB were calculated using normal BMI (18.5-24.9 kg/m(2)) as reference. Age, education, marital status, income, smoking, parity, previous PTB and pregnancy weight gain were included as covariates in logistic regression.No significant differences were noted in the OR for PTB among different BMI categories when women of different ethnicity were combined. Odds of PTB were greater in obese than in normal weight Caucasian women, even after adjusting for confounders (AOR = 1.84, 95%CI [1.15, 2.95]). Obese African American women had a decreased crude OR for PTB, although this was not significant after adjusting for confounders (AOR = 0.72, 95%CI [0.38, 1.40]). the odds for early PTB (< 32 weeks) were decreased in obese compared with normal weight African American women (OR = 0.23, 95%CI [0.08, 0.70]), whereas they were increased in obese compared with normal weight Caucasian women (OR = 2.30, 95%CI [1.32, 4.00]).The risk for PTB in women with different pre-pregnancy BMI categories differs according to ethnicity.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.affiliationCentennial Womens Hosp, Perinatal Res Ctr, Nashville, TN USA
dc.description.affiliationWorld Hlth Org, Dept Reprod Hlth & Res, Geneva, Switzerland
dc.description.affiliationVanderbilt Univ, Ctr Human Genet Res, Nashville, TN USA
dc.description.affiliationEmory Univ, Dept Epidemiol, Atlanta, GA 30322 USA
dc.description.affiliationUniv Texas Med Branch Galveston, Dept Obstet & Gynecol, Div Maternal Fetal Med Perinatal Res, Galveston, TX USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipThrasher Research Funds
dc.description.sponsorshipIDThrasher Research Funds: 02818-3
dc.description.sponsorshipIDThrasher Research Funds: 21FY08-557
dc.format.extent959-966
dc.identifierhttp://dx.doi.org/10.1007/s00404-011-2102-8
dc.identifier.citationArchives of Gynecology and Obstetrics. Heidelberg: Springer Heidelberg, v. 285, n. 4, p. 959-966, 2012.
dc.identifier.doi10.1007/s00404-011-2102-8
dc.identifier.issn0932-0067
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34748
dc.identifier.wosWOS:000301543300011
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofArchives of Gynecology and Obstetrics
dc.rightsAcesso restrito
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectPremature birthen
dc.subjectBody mass indexen
dc.subjectNutritionen
dc.subjectEthnic groupsen
dc.subjectAfrican Americansen
dc.subjectEuropean continental ancestry groupen
dc.titleEthnic disparity in spontaneous preterm birth and maternal pre-pregnancy body mass indexen
dc.typeArtigo
Arquivos
Coleções
EPM - Artigos