International prescribing practices in obsessive-compulsive disorder (OCD)

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dc.citation.issue4
dc.citation.volume31
dc.contributor.authorBrakoulias, Vlasios
dc.contributor.authorStarcevic, Vladan
dc.contributor.authorBelloch, Amparo
dc.contributor.authorDell'Osso, Liliana
dc.contributor.authorFerrao, Ygor A.
dc.contributor.authorFontenelle, Leonardo F.
dc.contributor.authorLochner, Christine
dc.contributor.authorMarazziti, Donatella
dc.contributor.authorMartin, Andrew
dc.contributor.authorMatsunaga, Hisato
dc.contributor.authorMiguel, Euripedes C.
dc.contributor.authorReddy, Y. C. Janardhan
dc.contributor.authordo Rosario, Maria C. [UNIFESP]
dc.contributor.authorShavitt, Roseli G.
dc.contributor.authorSundar, Arumugham Shyam
dc.contributor.authorStein, Dan Joseph
dc.contributor.authorViswasam, Kirupamani
dc.coverageHoboken
dc.date.accessioned2020-08-14T13:44:26Z
dc.date.available2020-08-14T13:44:26Z
dc.date.issued2016
dc.description.abstractObjectivesTo assess rates of psychotropic medication use in patients with obsessive-compulsive disorder (OCD) in seven different countries on five continents and to compare these with international treatment guidelines. MethodsResearchers in the field of OCD were invited to contribute summary statistics on the characteristics of their patients with OCD and on their incidence of psychotropic use. Consistency of summary statistics across countries was evaluated. ResultsThe data came from Brazil (n=955), Italy (n=750), South Africa (n=555), Japan (n=382), Australia (n=213), India (n=202) and Spain (n=82). The majority (77.9%en
dc.description.abstractn=2445) of the total sample of 3139 participants received a psychotropic medication. Consistent with international guidelines, selective serotonin reuptake inhibitors (SSRIs) were most commonly used (73.5%, n=1796), but their use ranged from 59% in Australia to 96% in Japan. Clomipramine use varied from 5% in Japan and South Africa to 26% in India and Italy. Atypical antipsychotic use ranged from 12% in South Africa to 50% in Japan. ConclusionsPharmacotherapy for OCD varied significantly across sites. Prospective studies are required to determine the cultural, pharmacoeconomic and pharmacogenomic factors that may play a role in the variation in prescribing practices internationally and whether these variations influence treatment outcomes. Copyright (c) 2016 John Wiley & Sons, Ltd.en
dc.description.affiliationUniv Sydney, Dept Psychiat, Sydney, NSW, Australia
dc.description.affiliationNepean Hosp, Sydney Med Sch Nepean, Discipline Psychiat, Penrith, NSW, Australia
dc.description.affiliationUniv Valencia, Fac Psychol, Res Unit Obsessive Compuls & Related Disorders, Dept Personal Psychol,ITOC, E-46003 Valencia, Spain
dc.description.affiliationUniv Pisa, Dipartmento Farm, Sect Psychiat, Dipartimento Med Clin & Sperimentale, I-56100 Pisa, Italy
dc.description.affiliationFed Univ Hlth Sci Porto Alegre, Dept Psychiat, Porto Alegre, RS, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Dept Psychiat & Legal Med, BR-21941 Rio De Janeiro, Brazil
dc.description.affiliationMonash Univ, Monash Inst Cognit & Clin Neurosci, DOr Inst Res & Educ, Clayton, Vic 3800, Australia
dc.description.affiliationUniv Stellenbosch, Dept Psychiat, MRC Unit Anxiety Disorders, Cape Town, South Africa
dc.description.affiliationUniv Sydney, NHMRC Clin Trials Ctr, Sydney, NSW, Australia
dc.description.affiliationHyogo Coll Med, Dept Neuropsychiat, Nishinomiya, Hyogo, Japan
dc.description.affiliationUniv Sao Paulo, Sch Med, Dept & Inst Psychiat, BR-05508 Sao Paulo, Brazil
dc.description.affiliationNatl Inst Mental Hlth & Neurosci NIMHANS, Dept Psychiat, Bengaluru, India
dc.description.affiliationUniv Fed Sao Paulo, Dept Psychiat, Child & Adolescent Psychiat Unit UPIA, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Psychiat, Child & Adolescent Psychiat Unit UPIA, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipNepean Medical Research Foundation
dc.description.sponsorshipPfizer Neuroscience Grant Programme
dc.description.sponsorshipSpanish MINECO
dc.description.sponsorshipUniversity of Sydney
dc.description.sponsorshipIDSpanish MINECO: PSI2013-44733-R
dc.format.extent319-324
dc.identifierhttp://dx.doi.org/10.1002/hup.2541
dc.identifier.citationHuman Psychopharmacology-Clinical And Experimental. Hoboken, v. 31, n. 4, p. 319-324, 2016.
dc.identifier.doi10.1002/hup.2541
dc.identifier.issn0885-6222
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57668
dc.identifier.wosWOS:000379939200007
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofHuman Psychopharmacology-Clinical And Experimental
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectcross-cultural studyen
dc.subjectobsessive-compulsive disorderen
dc.subjectpharmacotherapyen
dc.subjectmedicationen
dc.subjectselective serotonin re-uptake inhibitorsen
dc.subjectantipsychoticsen
dc.subjectbenzodiazepinesen
dc.titleInternational prescribing practices in obsessive-compulsive disorder (OCD)en
dc.typeinfo:eu-repo/semantics/article
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