Relevant aspects of imaging in the diagnosis and management of gout

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dc.citation.issue1
dc.citation.volume57
dc.contributor.authorFernandes, Eloy de Avila [UNIFESP]
dc.contributor.authorBergamaschi, Samuel Brighenti
dc.contributor.authorRodrigues, Tatiane Cantarelli
dc.contributor.authorDias, Gustavo Coelho
dc.contributor.authorMalmann, Ralff
dc.contributor.authorRamos, Germano Martins
dc.contributor.authorMonteiro, Soraya Silveira [UNIFESP]
dc.coverageNew York
dc.date.accessioned2020-07-31T12:46:47Z
dc.date.available2020-07-31T12:46:47Z
dc.date.issued2017
dc.description.abstractGout is an inflammatory arthritis characterized by the deposition of monosodium urate crystals in the synovial membrane, articular cartilage and periarticular tissues leading to inflammation. Men are more commonly affected, mainly after the 5th decade of life. Its incidence has been growing with the population aging. In the majority of the cases, the diagnosis is made by clinical criteria and synovial fluid analysis, in search for monosodium urate crystals. Nonetheless, gout may sometimes have atypical presentations, complicating the diagnosis. In these situations, imaging methods have a fundamental role, aiding in the diagnostic confirmation or excluding other possible differential diagnosis. Conventional radiographs are still the most commonly used method in gout patients' evaluationen
dc.description.abstractnevertheless, this is not a sensitive method, since it detect only late alterations. In the last years, there have been several advances in imaging methods for gout patients. Ultrasound has shown a great accuracy in the diagnosis of gout, identifying monosodium urate deposits in the synovial membrane and articular cartilage, in detecting and characterizing tophi and in identifying tophaceous tendinopathy and enthesopathy. Ultrasound has also been able to show crystal deposition in patients with articular pain in the absence of a classical gout crisis. Computed tomography is an excellent method for detecting bone erosions, being useful in spine involvement. Dual-energy CT is a new method able to provide information about the chemical composition of tissues, with high accuracy in the identification of monosodium urate deposits, even in the early stages of the disease and in cases of difficult characterization. Magnetic resonance imaging is useful in the evaluation of deep tissues not accessible by ultrasound. Besides the diagnosis, with the emergence of new drugs that aim to reduce tophaceous burden, imaging methods have become useful tools in monitoring the treatment of patients with gout. (C) 2016 Published by Elsevier Editora Ltda.en
dc.description.affiliationHosp Servidor Publ Estadual Iamspe, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo Unifesp, Dept Diagnost Imagem, Sao Paulo, SP, Brazil
dc.description.affiliationHosp Coracao HCor, HCor Teleimagem, Sao Paulo, SP, Brazil
dc.description.affiliationHosp Estadual Vila Alpina, Sao Paulo, SP, Brazil
dc.description.affiliationHSPE FMO, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo (Unifesp), Departamento de Diagnóstico por Imagem, São Paulo, SP, Brasil
dc.description.sourceWeb of Science
dc.format.extent64-72
dc.identifierhttp://dx.doi.org/10.1016/j.rbre.2016.05.001
dc.identifier.citationRevista Brasileira De Reumatologia. New York, v. 57, n. 1, p. 64-72, 2017.
dc.identifier.doi10.1016/j.rbre.7016.05.001
dc.identifier.fileWOS000396445600009.pdf
dc.identifier.issn0482-5004
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56366
dc.identifier.wosWOS:000396445600009
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofRevista Brasileira De Reumatologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGouten
dc.subjectUltrasounden
dc.subjectMagnetic resonance imagingen
dc.subjectDual-energy computed tomographyen
dc.titleRelevant aspects of imaging in the diagnosis and management of gouten
dc.titleAspectos relevantes do diagnóstico e seguimento por imagem na gotapt
dc.typeinfo:eu-repo/semantics/article
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