Skeletal muscle structure and function in response to electrical stimulation in moderately impaired COPD patients

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dc.contributor.authorDal Corso, Simone [UNIFESP]
dc.contributor.authorNápolis, Lara Maris [UNIFESP]
dc.contributor.authorMalaguti, Carla [UNIFESP]
dc.contributor.authorGimenes, Ana Cristina Oliveira [UNIFESP]
dc.contributor.authorAlbuquerque, André Luis Pereira de
dc.contributor.authorNogueira, Cristiano Rabelo [UNIFESP]
dc.contributor.authorDe Fuccio, Marcelo Bicalho
dc.contributor.authorPereira, Roberto Dias Batista [UNIFESP]
dc.contributor.authorOliveira, Acary Souza Bulle [UNIFESP]
dc.contributor.authorMcFarlane, Niall
dc.contributor.authorNery, Luiz Eduardo [UNIFESP]
dc.contributor.authorNeder, Jose Alberto [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Glasgow
dc.date.accessioned2016-01-24T13:48:44Z
dc.date.available2016-01-24T13:48:44Z
dc.date.issued2007-06-01
dc.description.abstractStudy objective: To determine the structural and functional consequences of high-frequency neuromuscular electrical stimulation (hf-NMES) in a group of moderately impaired outpatients with chronic obstructive pulmonary disease (COPD).Design: A prospective, cross-over randomized trial.Setting: An university-based, tertiary center.Patients and materials: Seventeen patients (FEV1 = 49.6 +/- 13.4% predicted, Medical Research Council dyspnoea grades II-III) underwent 6-weeks hf-NMES (50 Hz) and sham stimulation of the quadriceps femoris in a randomized, cross-over design. Knee strength was measured by isokinetic dynamometry (peak torque) and leg muscle mass (LMM) by DEXA; in addition, median cross-sectional area (CSA) of type I and fibres and capillary-fibre ratio were evaluated in the vastus lateralis. the 6-min walking distance (6MWD) was also determined.en
dc.description.affiliationUniversidade Federal de São Paulo, UNIFESP, Pulm Funct & Clin Exercise Physiol Unit, SEFIC,Div Resp Dis,Dept Med, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, UNIFESP, Neuromusc Div, São Paulo, Brazil
dc.description.affiliationUniv Glasgow, Inst Biomed & Life Sci, Glasgow, Lanark, Scotland
dc.description.affiliationUnifespUniversidade Federal de São Paulo, UNIFESP, Pulm Funct & Clin Exercise Physiol Unit, SEFIC,Div Resp Dis,Dept Med, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, UNIFESP, Neuromusc Div, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1236-1243
dc.identifierhttp://dx.doi.org/10.1016/j.rmed.2006.10.023
dc.identifier.citationRespiratory Medicine. London: W B Saunders Co Ltd, v. 101, n. 6, p. 1236-1243, 2007.
dc.identifier.doi10.1016/j.rmed.2006.10.023
dc.identifier.fileWOS000247313000025.pdf
dc.identifier.issn0954-6111
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29756
dc.identifier.wosWOS:000247313000025
dc.language.isoeng
dc.publisherW B Saunders Co Ltd
dc.relation.ispartofRespiratory Medicine
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectchronic obstructive pulmonary diseaseen
dc.subjectelectrical stimulationen
dc.subjectskeletal muscleen
dc.subjectrehabilitationen
dc.subjectstrengthen
dc.titleSkeletal muscle structure and function in response to electrical stimulation in moderately impaired COPD patientsen
dc.typeinfo:eu-repo/semantics/article
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