Hormonal influence on periurethral vessels in postmenopausal incontinent women using Doppler velocimetry analysis

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dc.contributor.authorJarmy-Di Bella, Z. I. K.
dc.contributor.authorGirao, M. J. B. C.
dc.contributor.authorDi Bella, V.
dc.contributor.authorSartori, M. G. F.
dc.contributor.authorSzejnfeld, J.
dc.contributor.authorBaracat, E. C. [UNIFESP]
dc.contributor.authorLima, G. R.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:41:59Z
dc.date.available2016-01-24T12:41:59Z
dc.date.issued2007-03-20
dc.description.abstractThe lack of estrogen affects the urinary tract mainly by diminishing vascular, muscular and epithelial trophism, resulting in negative effects on continence in postmenopausal women.Objective: Study the effect of hormone therapy (estrogen and progesterone) in periurethral vessels detected by Doppler velocimetric analysis using, as parameters, the number of vessels, resistance and pulsatility indexes, as well as the minimum diastolic value.Methods: Thirty-eight postmenopausal women with stress urinary incontinence were randomized into two groups. the first consisted of women receiving 3 months of estrogen therapy previous to 3 months of continuous estrogen and progesterone combined therapy. the second comprised of women receiving 3 months of continuous estrogen and progesterone therapy. Periurethral Doppler velocimetric analysis was done before hormone administration and during treatment in both groups.Results: We observed a statistically significant increased number of periurethral vessels during treatment in both groups. There was an increase in value of the mean minimum diastolic value during estrogen and progesterone therapy in Group 2. the resistance indexes diminished in both groups. However, they were not statistically significant.Conclusion: Hormonal therapy of short duration (3-6 months) had a positive effect on the urethral continence mechanism increasing the number of periurethral vessels either with estrogen alone or combined therapy (estrogen and progesterone). (c) 2006 Elsevier Ireland Ltd. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Gynecol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Gynecol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent297-302
dc.identifierhttp://dx.doi.org/10.1016/j.maturitas.2006.09.004
dc.identifier.citationMaturitas. Clare: Elsevier B.V., v. 56, n. 3, p. 297-302, 2007.
dc.identifier.doi10.1016/j.maturitas.2006.09.004
dc.identifier.issn0378-5122
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29592
dc.identifier.wosWOS:000244971200008
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofMaturitas
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectDoppleren
dc.subjectultrasounden
dc.subjectstress urinary incontinenceen
dc.subjecthormone therapyen
dc.titleHormonal influence on periurethral vessels in postmenopausal incontinent women using Doppler velocimetry analysisen
dc.typeinfo:eu-repo/semantics/article
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