Genotoxicity Induced by Dental Materials: A Comprehensive Review
Data
2017
Autores
Ribeiro, Daniel Araki 
Yujra, Veronica Quispe
Moura, Carolina Foot Gomes de
Handan, Bianca Andrade
Viana, Milena de Barros
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Genotoxicity is the capacity of an agent to produce damage in the DNA molecule. Considering the strong evidence for a relationship between genetic damage and carcinogenesis, evaluation of genotoxicity induced by dental materials is necessary for elucidating the true health risks to patients and professionals. The purpose of this article was to provide a comprehensive review of genotoxicity induced by dental materials. All published data showed some evidence of genotoxicity, especially related to dental bleaching, restorative materials and endodontic compounds. Certainly, such information will be added to that already established for regulatory purposes as a safe way to promote oral healthcare and prevent oral carcinogenesis.
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Anticancer Research. Athens, v. 37, n. 8, p. 4017-4024, 2017.