Clinical expression in 7 patients with malt lymphoma of the conjunctiva
Data
1998-01-01
Autores
Oliveira, José Salvador Rodrigues de 
Colleoni,Gisele Wally Braga
Borducchi, Davimar Miranda Maciel
Rigueiro, Moacyr Pezati
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Problem: Lymphomas of conjunctiva are more common than is believed and immunohistologic analysis is able to distinguish benign and malignant lymphoid infiltrates. Methods: We analyzed seven cases of primary lymphoma of conjunctiva treated between November/1989 and April/1994. There were six females and one male with median age of 50 years (range 33-76 years). Results: Six patients were stage IE and one was IIE. At diagnosis, all but one had unilateral compromise of conjunctiva. All patients were classified as MALT lymphoma and six of them were positive for lambda light chain. Four patients were treated with combination of chemotherapy and bilateral radiotherapy and two received radiotherapy alone. One patient had bilateral relapse 12 months after chemotherapy alone and was successfully treated with radiotherapy. All cases treated with combined therapy achieved complete remission. Conclusion: Based on this experience, we suggest that combined treatment with chemotherapy and bilateral radiotherapy can prevent local relapse.
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Cancer Research Therapy & Control. Reading: Harwood Acad Publ Gmbh, v. 5, n. 4, p. 319-322, 1998.