Radiotherapy for early glottic cancer and salvage surgery after recurrence
dc.contributor.author | Pontes, Paulo [UNIFESP] | |
dc.contributor.author | Brasil, Osiris de Oliveira Campones do [UNIFESP] | |
dc.contributor.author | Amorim Filho, Francisco de Souza [UNIFESP] | |
dc.contributor.author | Moraes, Bruno Teixeira de [UNIFESP] | |
dc.contributor.author | Pontes, Antonio [UNIFESP] | |
dc.contributor.author | Caporrino Neto, José [UNIFESP] | |
dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
dc.date.accessioned | 2015-06-14T13:43:08Z | |
dc.date.available | 2015-06-14T13:43:08Z | |
dc.date.issued | 2011-06-01 | |
dc.description.abstract | Early glottic cancer can be effectively treated with radiation or surgery, but recurrence is a possibility when using any of the treatment modalities. AIM: To assess the outcome of radiotherapy as initial treatment in the control of squamous cell carcinoma of vocal cord (T1) and the effectiveness of salvage surgery (endoscopic or open) after treatment failure. MATERIALS AND METHODS: A retrospective study was based on the analysis of medical records from 43 patients with T1 squamous cell carcinoma of the glottis, radiotherapy as initial treatment and follow-up period of five years. RESULTS: The rate of recurrence after radiotherapy was 30.2% of the cases, mean diagnosis interval was 29.5 months. As an option for salvage treatment, patients underwent open partial laryngectomy or endoscopic surgery with control rates of 77.7% and 25% respectively. CONCLUSION: Our cases showed high rates of recurrence after radiotherapy and open partial laryngectomy was more effective for the salvage surgery. | en |
dc.description.abstract | O câncer glótico inicial pode ser efetivamente tratado com radioterapia ou com cirurgia, contudo a recidiva é uma possibilidade quando utilizada qualquer uma das formas terapêuticas. OBJETIVO: Avaliar o resultado da radioterapia como tratamento inicial no controle do carcinoma epidermoide de prega vocal (T1) e a eficácia do resgate cirúrgico (endoscópico ou externo) após a falha deste tratamento. MATERIAL E MÉTODO: Foi realizado estudo retrospectivo a partir da análise de prontuários de 43 pacientes portadores de carcinoma epidermoide da glote com estadiamento T1, submetidos à radioterapia como tratamento inicial e com seguimento mínimo de cinco anos. RESULTADOS: A taxa de recidiva após radioterapia foi de 30,2% dos casos, com intervalo médio de diagnóstico de 29,5 meses. Como opção para tratamento de resgate, os pacientes foram submetidos à laringectomia parcial externa ou endoscópica com taxa de controle de 77,7% e 25%, respectivamente. CONCLUSÃO: Nossos casos apresentaram altas taxas de recidiva após radioterapia e a laringectomia parcial externa mostrou-se mais eficaz para o resgate cirúrgico. | pt |
dc.description.affiliation | Federal University of São Paulo Department of Otorhinolaryngology and Head and Neck Surgery | |
dc.description.affiliationUnifesp | UNIFESP, Department of Otorhinolaryngology and Head and Neck Surgery | |
dc.description.source | SciELO | |
dc.format.extent | 299-302 | |
dc.identifier | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000300005&lng=en&nrm=iso&tlng=pt | |
dc.identifier.citation | Brazilian Journal of Otorhinolaryngology. Associação Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial, v. 77, n. 3, p. 299-302, 2011. | |
dc.identifier.doi | 10.1590/S1808-86942011000300005 | |
dc.identifier.file | S1808-86942011000300005-en.pdf | |
dc.identifier.file | S1808-86942011000300005-pt.pdf | |
dc.identifier.issn | 1808-8694 | |
dc.identifier.scielo | S1808-86942011000300005 | |
dc.identifier.uri | http://repositorio.unifesp.br/handle/11600/6512 | |
dc.identifier.wos | WOS:000293580800005 | |
dc.language.iso | eng | |
dc.publisher | Associação Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial | |
dc.relation.ispartof | Brazilian Journal of Otorhinolaryngology | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | laryngeal neoplasms | en |
dc.subject | laryngectomy | en |
dc.subject | neoplasm recurrence local | en |
dc.subject | radiotherapy | en |
dc.subject | salvage therapy | en |
dc.subject | laringectomia | pt |
dc.subject | neoplasias laríngeas | pt |
dc.subject | radioterapia | pt |
dc.subject | recidiva local de neoplasia | pt |
dc.subject | terapia de salvação | pt |
dc.title | Radiotherapy for early glottic cancer and salvage surgery after recurrence | en |
dc.title.alternative | Radioterapia para câncer glótico inicial e resgate cirúrgico após recorrência | pt |
dc.type | info:eu-repo/semantics/article |