Analysis of Risk Factors for Extubation Failure in Subjects Submitted to Non-Emergency Elective Intracranial Surgery

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dc.contributor.authorVidotto, Milena Carlos [UNIFESP]
dc.contributor.authorSogame, Luciana Carrupt Machado [UNIFESP]
dc.contributor.authorGazzotti, Mariana Rodrigues [UNIFESP]
dc.contributor.authorPrandini, Mirto Nelson [UNIFESP]
dc.contributor.authorJardim, Jose Roberto [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionEscola Super Ciencias Santa Casa Misericordia Vit
dc.date.accessioned2016-01-24T14:28:03Z
dc.date.available2016-01-24T14:28:03Z
dc.date.issued2012-12-01
dc.description.abstractBACKGROUND: Extubation failure is defined as the re-institution of respiratory support ranging from 24 to 72 hours following scheduled extubation and occurs in 2% to 25% of extubated patients. the aim of this study was to determine clinical and surgical risk factors that may predict extubation failure in patients submitted to non-emergency intracranial surgery. METHODS: This was a prospective observational cohort study. the study was carried out on 317 subjects submitted to non-emergency intracranial surgery for tumors, aneurysms, and arteriovenous malformation. Preoperative assessment was performed and subjects were followed up for the determination of extubation failure until either discharge from hospital or death. RESULTS: Twenty-six (8.2%) of the 317 subjects experienced extubation failure following surgery. the following variables were considered for the multivariate analysis: level of consciousness at the time of extubation, duration of mechanical ventilation prior to extubation, sex and the use of intraoperative mannitol. the multivariate analysis determined that the most important variable for extubation failure was the level of consciousness at the time of extubation (P = .001), followed by female sex, which also showed to be significant (P = .006). CONCLUSIONS: Lower level of consciousness (GCS 8T-10T) and female sex were considered risk factors for extubation failure in subjects submitted to elective intracranial surgery.en
dc.description.affiliationUniversidade Federal de São Paulo, Disciplina Pneumol, Div Resp, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Physiotherapy, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Neurosurg, BR-04023062 São Paulo, Brazil
dc.description.affiliationEscola Super Ciencias Santa Casa Misericordia Vit, Dept Physiotherapy, Vitoria, Espirito Santo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Disciplina Pneumol, Div Resp, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Physiotherapy, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Neurosurg, BR-04023062 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent2059-2066
dc.identifierhttp://rc.rcjournal.com/content/57/12/2059.short
dc.identifier.citationRespiratory Care. Irving: Daedalus Enterprises Inc, v. 57, n. 12, p. 2059-2066, 2012.
dc.identifier.doi10.4187/respcare.01039
dc.identifier.issn0020-1324
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35537
dc.identifier.wosWOS:000312057300010
dc.language.isoeng
dc.publisherDaedalus Enterprises Inc
dc.relation.ispartofRespiratory Care
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectneurosurgeryen
dc.subjectcraniotomyen
dc.subjectventilator weaningen
dc.subjectintratracheal intubationen
dc.subjectrisk factorsen
dc.subjectpostoperative perioden
dc.titleAnalysis of Risk Factors for Extubation Failure in Subjects Submitted to Non-Emergency Elective Intracranial Surgeryen
dc.typeinfo:eu-repo/semantics/article
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