The Role of Canonical WNT Signaling Pathway in Oral Carcinogenesis: A Comprehensive Review

Página do item simplificado
dc.contributor.authorNoguti, Juliana [UNIFESP]
dc.contributor.authorMoura, Carolina Foot Gomes de [UNIFESP]
dc.contributor.authorHossaka, Thais Ayako [UNIFESP]
dc.contributor.authorFranco, Marcello Fabiano de [UNIFESP]
dc.contributor.authorOshima, Celina Tizuko Fujiyama [UNIFESP]
dc.contributor.authorDedivitis, Rogério Aparecido [UNIFESP]
dc.contributor.authorRibeiro, Daniel Araki [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionAna Costa Hosp & Santa Casa Misericordia Santos
dc.date.accessioned2018-06-15T13:50:15Z
dc.date.available2018-06-15T13:50:15Z
dc.date.issued2012-03-01
dc.description.abstractOral cancer is a common neoplasm worldwide. The incidence and mortality have also increased in recent decades. It is characterized by poor prognosis and a low survival rate despite sophisticated surgical and radiotherapeutic modalities. The WNTs comprise a large family of highly conserved growth factors associated with a number of functions. In this review, we focus largely on the canonical pathway, revealing the recent findings, in oral cancer research, thereby raising our understanding of the mechanisms of this crucial signaling in several cellular activities.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Biosci, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Pathol, Sao Paulo, Brazil
dc.description.affiliationAna Costa Hosp & Santa Casa Misericordia Santos, Dept Head & Neck Surg, Santos, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Biosci, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Pathol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent873-878
dc.identifierhttps://ar.iiarjournals.org/content/32/3/873.long
dc.identifier.citationAnticancer Research. Athens: Int Inst Anticancer Research, v. 32, n. 3, p. 873-878, 2012.
dc.identifier.issn0250-7005
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/42598
dc.identifier.wosWOS:000301619200024
dc.language.isoeng
dc.publisherInt Inst Anticancer Research
dc.relation.ispartofAnticancer Research
dc.rightsAcesso aberto
dc.subjectWNTen
dc.subjectOral canceren
dc.subjectApoptosisen
dc.subjectReviewen
dc.titleThe Role of Canonical WNT Signaling Pathway in Oral Carcinogenesis: A Comprehensive Reviewen
dc.typeResenha
Arquivos
Coleções
ISS - Outras produções
EPM - Outras produções